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Chikaaki Motoda

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Articles 34
Citations 290
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Recent Articles
1.
Ito S, Hashimoto H, Yamakawa H, Kusumoto D, Akiba Y, Nakamura T, et al.
Nat Commun . 2022 Sep; 13(1):5409. PMID: 36109509
Failure of the right ventricle plays a critical role in any type of heart failure. However, the mechanism remains unclear, and there is no specific therapy. Here, we show that...
2.
Ikeuchi Y, Ochi H, Motoda C, Tokuyama T, Okubo Y, Okamura S, et al.
PLoS One . 2022 May; 17(5):e0261390. PMID: 35617207
Background: Brugada syndrome (BrS) can be diagnosed by a type 1 BrS tracing in a 12-lead electrocardiogram (ECG). However, there are daily variations in the ECGs of BrS patients, which...
3.
Okubo Y, Nakano Y, Ochi H, Onohara Y, Tokuyama T, Motoda C, et al.
Heart Rhythm . 2020 Jan; 17(5 Pt A):699-705. PMID: 31931171
Background: Atrial fibrillation (AF) has a genetic basis, and environmental factors can modify its actual pathogenesis. Objective: The purpose of this study was to construct a combined risk assessment method...
4.
Amioka M, Nakano Y, Ochi H, Onohara Y, Sairaku A, Tokuyama T, et al.
PLoS One . 2019 Mar; 14(3):e0213208. PMID: 30840693
Background: Atrial fibrillation (AF) recurrence after radiofrequency catheter ablation (RFCA) still remains a serious issue. Ca2+ handling has a considerable effect on AF recurrence. The histidine-rich calcium-binding protein (HRC) genetic...
5.
Kawase T, Ueda H, Watanabe N, Motoda C, Takeda R, Mito S, et al.
J Cardiol Cases . 2018 Dec; 2(3):e154-e158. PMID: 30532818
Stenosis of the left main coronary artery (LMCA) due to extrinsic compression, producing symptoms of myocardial ischemia, is called left main compression syndrome. We report on a 43-year-old male with...
6.
Tomomori S, Nakano Y, Ochi H, Onohara Y, Sairaku A, Tokuyama T, et al.
Sci Rep . 2018 Oct; 8(1):14565. PMID: 30275471
Genome-wide association studies have reported a strong association of the single nucleotide polymorphism (SNP) rs6817105 (T > C) on chromosome 4q25 with atrial fibrillation (AF), but phenotype alterations conferred by...
7.
Tomomori S, Nakano Y, Ochi H, Onohara Y, Sairaku A, Tokuyama T, et al.
PLoS One . 2018 Sep; 13(9):e0203281. PMID: 30180182
Introduction: The single nucleotide polymorphism (SNP) rs2106261 in the transcription factor gene ZFHX3 (16q22), a major regulator of inflammation, has been reported linking to atrial fibrillation (AF) by genome-wide association...
8.
Nakano Y, Ochi H, Sairaku A, Onohara Y, Tokuyama T, Motoda C, et al.
Circ Genom Precis Med . 2018 Jul; 11(7):e001980. PMID: 29987112
Background: Tachycardia-induced cardiomyopathy (TIC) is a reversible cardiomyopathy induced by tachyarrhythmia, and the genetic background of the TIC is not well understood. The hyperpolarization-activated cyclic nucleotide-gated channel gene is highly...
9.
Matsumura H, Nakano Y, Ochi H, Onohara Y, Sairaku A, Tokuyama T, et al.
J Biomed Sci . 2017 Dec; 24(1):91. PMID: 29202755
Background: A common SCN5A polymorphism H558R (c.1673 A > G, rs1805124) improves sodium channel activity in mutated channels and known to be a genetic modifier of Brugada syndrome patients (BrS)....
10.
Saito Y, Kunitomi A, Seki T, Tohyama S, Kusumoto D, Takei M, et al.
FEBS Lett . 2017 Aug; 591(18):2879-2889. PMID: 28805244
The expression of pluripotency genes fluctuates in a population of embryonic stem (ES) cells and the fluctuations in the expression of some pluripotency genes correlate. However, no correlation in the...