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Chih-Li Lin

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Articles 74
Citations 1068
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Recent Articles
1.
Hsu L, Lin C, Pan M, Chen W
Environ Toxicol . 2025 Jan; PMID: 39865447
The epithelial-mesenchymal transition (EMT) assists in the acquisition of invasiveness, relapse, and resistance in non-small cell lung cancer (NSCLC) and can be caused by the signaling of transforming growth factor-β1...
2.
Kuo C, Tsou S, Kornelius E, Chan K, Chang K, Li J, et al.
Cell Mol Life Sci . 2025 Jan; 82(1):39. PMID: 39779525
Background: Diabetes is a primary contributor to diabetic cardiomyopathy (DbCM), which is marked by metabolic imbalances such as elevated blood glucose and lipid levels, leading to significant structural and functional...
3.
Lin S, Chang C, Tsou S, Chiu P, Cheng J, Hung H, et al.
Int J Mol Sci . 2024 Nov; 25(22). PMID: 39596182
Dementia with Lewy bodies (DLB) is a progressive neurodegenerative disorder marked by the accumulation of α-synuclein (αSyn), often co-existing with amyloid β (Aβ) pathology. Current treatments are largely symptomatic, highlighting...
4.
Tsou S, Lin S, Chen W, Hung H, Liao C, Kornelius E, et al.
Biomedicines . 2024 Jul; 12(7). PMID: 39062020
Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by excessive fat accumulation in the liver. Intracellular oxidative stress induced by lipid accumulation leads to various hepatocellular injuries including fibrosis. However,...
5.
Lin S, Tsou S, Kuo C, Chen W, Wu K, Lin C, et al.
Int J Mol Sci . 2023 Jun; 24(12). PMID: 37373436
Obesity is strongly associated with insulin sensitivity in type 2 diabetes (T2D), mainly because free fatty acids (FFAs) are released from excess fat tissue. Long-term exposure to high levels of...
6.
Kornelius E, Tsou S, Chang C, Ho Y, Lin S, Chen W, et al.
Biomolecules . 2022 Oct; 12(10). PMID: 36291547
Diabetic neuropathy (DN) is a type of sensory nerve damage that can occur in patients with diabetes. Although the understanding of pathophysiology is incomplete, DN is often associated with structural...
7.
Li J, Cheng P, Huang C, Jian L, Wu Y, Lin C
Front Endocrinol (Lausanne) . 2022 Sep; 13:935561. PMID: 36157468
Background: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder involving progressive pancreatic dysfunction. A substantial proportion of patients with T2DM cannot achieve euglycemia despite pharmacologic therapy. Preceding clinical...
8.
Lin C, Zheng T, Tsou S, Chang H, Tseng L, Yu C, et al.
Behav Brain Res . 2022 Aug; 435:114035. PMID: 35926562
Dementia with Lewy bodies (DLB), a highly prevalent neurodegenerative disorder, causes motor and cognitive deficits. The main pathophysiologies of DLB are glutamate excitotoxicity and accumulation of Lewy bodies comprising α-synuclein...
9.
Chen W, Tsai J, Hsu L, Lin C, Hong H, Pan M
J Food Drug Anal . 2022 Jun; 29(1):98-112. PMID: 35696220
The cancer-preventive activities of quercetin have been extensively studied in invasive breast cancer; however, the role of quercetin on triple-negative breast cancer (TNBC) with overexpression of insulin-like growth factor-1 receptor...
10.
Peng C, Ker Y, Li H, Tsou S, Lin C, Huang C
PLoS One . 2022 Mar; 17(3):e0265444. PMID: 35290413
Nonalcoholic fatty liver disease (NAFLD) is recognized as the liver component of metabolic syndrome. The regulation of hepatic lipid should be emphasized to prevent accompanying illness. As AMP-activated protein kinase...