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Chih-Hung Chiang

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Articles 33
Citations 231
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Recent Articles
1.
Lee H, Chiang C, Hsieh J, Lin S, Chen J, Chang T
Biomed Pharmacother . 2025 Mar; 185:117952. PMID: 40068488
The accumulation of uremic toxins in circulation contributes to the cardiovascular diseases that result from chronic kidney disease (CKD). Indoxyl sulfate (IS), which is a protein-bound uremic toxin, promotes cardiovascular...
2.
Wang W, Liu Y, Lo T, Hsu F, Chiang C
In Vivo . 2025 Feb; 39(2):669-682. PMID: 40010952
Background/aim: Bladder cancer is a prevalent malignancy, ranging from superficial forms to more aggressive types that invade the muscle and require extensive treatment. Imipramine, traditionally used as an antidepressant, has...
3.
Chiang C, Yang J, Liu W, Chang F, Yang C, Hsu K, et al.
Cancer Cell Int . 2025 Feb; 25(1):47. PMID: 39955573
Background: The persistent activation of the epidermal growth factor receptor (EGFR) leads to the activation of downstream oncogenic kinases and transcription factors, resulting in tumor progression and an increased resistance...
4.
Lan T, Chiang C, Chen J, Chang T
J Chin Med Assoc . 2025 Jan; PMID: 39789694
Tadalafil is a selective phosphodiesterase type 5 (PDE5) inhibitor commonly used for the treatment of erectile dysfunction and benign prostatic hyperplasia. Its mechanism of action involves the inhibition of PDE5,...
5.
Liu K, Tseng C, Wong S, Huang K, Chiang I, Huang C, et al.
Biomedicines . 2025 Jan; 12(12. PMID: 39767771
: We aimed to determine the proportion of bacterial etiology in pediatric acute epididymitis (AE) and to compare the predictive accuracy of C-reactive protein (CRP) and urinalysis. : Pediatric patients...
6.
Chang T, Li S, Tsai M, Chiang C, Chen C, Chen J
Clin Sci (Lond) . 2024 Nov; 138(22):1451-1466. PMID: 39503534
Acute kidney injury (AKI) increases the risk of chronic kidney disease (CKD). CXC motif chemokine ligand 5 (CXCL5) is up-regulated in kidney diseases. We aimed to investigate the direct effect...
7.
Chiang C, Lan T, Hsieh J, Lin S, Chen J, Chang T
J Agric Food Chem . 2024 Oct; 72(43):24130. PMID: 39425655
No abstract available.
8.
Chiang C, Lan T, Hsieh J, Lin S, Chen J, Chang T
J Agric Food Chem . 2024 Jul; 72(31):17444-17454. PMID: 39074384
Acute kidney injury (AKI), if not well controlled, may progress to chronic kidney disease (CKD). Diosgenin is a natural phytosteroid sapogenin from plants. This study aimed to investigate the mechanistic...
9.
Chang C, Yu P, Hsieh P, Hong J, Chiang C, Cheng H, et al.
J Chin Med Assoc . 2024 Jun; 87(7):678-685. PMID: 38829960
Background: Multiparametric magnetic resonance imaging (mpMRI) followed by MRI-targeted prostate biopsy is the current standard for diagnosing prostate cancer (PCa). However, studies evaluating the value of biomarkers, including prostate health...
10.
Chiang C, Chen C, Fang S, Lin S, Chen J, Chang T
Life Sci . 2023 Jun; 327:121863. PMID: 37331504
Aims: The enhancement of inflammation and reactive oxygen species leads to the damage of renal tubular cells in acute kidney injury (AKI), and the upregulation of inflammation increases the risk...