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Chien-Yu Lin

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Articles 554
Citations 5659
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Recent Articles
11.
Zhao Y, Andoh T, Charles F, Reddy P, Paul K, Goar H, et al.
bioRxiv . 2025 Jan; PMID: 39803490
VISTA is a key immune checkpoint receptor under investigation for cancer immunotherapy; however, its signaling mechanisms remain unclear. Here we identify a conserved four amino acid (NPGF) intracellular motif in...
12.
Zhao Z, Fetse J, Mamani U, Guo Y, Li Y, Patel P, et al.
Acta Biomater . 2024 Dec; 193:484-497. PMID: 39716541
Antibody-based checkpoint inhibitors have achieved great success in cancer immunotherapy, but their uncontrollable immune-related adverse events remain a major challenge. In this study, we developed a tumor-activated nanoparticle that is...
13.
Wu P, Huang C, Chang P, Lee T, Lin C, Chang J, et al.
Laryngoscope . 2024 Dec; PMID: 39714978
Objective: Post-irradiation sinonasal mucosa disease (SMD) is observed in patients with nasopharyngeal carcinoma (NPC) treated with radiotherapy (RT), leading to a detrimental impact on quality of life. This study aimed...
14.
Chen J, Park J, Lin C, Lai T, Kim D, Shin M, et al.
JMIR Public Health Surveill . 2024 Dec; 10:e63457. PMID: 39692345
Background: Recently, the phase angle (PhA) has emerged as an essential indicator of cellular health. Most studies have examined its association with physiological conditions, such as sarcopenia, frailty, and physical...
15.
Mamani U, Ibrahim M, Liu Y, Fetse J, Lin C, Kandel S, et al.
Pharm Res . 2024 Dec; 41(12):2275-2288. PMID: 39681781
Purpose: The PD-1/PD-L1 pathway is one of the most effective immune checkpoint pathways utilized for cancer immunotherapy. Despite the success of anti-PD-1/PD-L1 mAbs, there is growing interest in developing low...
16.
Lin C, Chang W, Su P, Kuo C, Yang J, Lin C, et al.
JAMA Netw Open . 2024 Dec; 7(12):e2448364. PMID: 39636639
Importance: Although it has been reported that osimertinib mesylate provides better survival benefits compared with first- or second-generation epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs), it remains unclear...
17.
Lin C, Lai T, Fang C, Hsueh M, Liao Y
BMC Geriatr . 2024 Nov; 24(1):938. PMID: 39538132
Background: Proximity to parks has been suggested as a factor influencing physical activity in older adults. However, it remains unclear the optimal distance between residences and parks for promoting physical...
18.
Chen H, Sung Y, Chen C, Weng S, Liou B, Yeung C, et al.
Sex Health . 2024 Nov; 21. PMID: 39509266
Background The protracted battle against coronavirus disease 2019 (COVID-19) has had a profound impact on various facets of society. The epidemiology of several diseases underwent alterations following the implementation of...
19.
Klibngern H, Kang C, Lee L, Ng S, Lin C, Fan K, et al.
Oral Oncol . 2024 Nov; 159:107102. PMID: 39488902
Background: The prognostic significance of margin-to-depth ratio (MDR) in oral cavity squamous cell carcinoma (OCSCC) remains unclear, particularly in comparison to traditional margin status. We aimed to examine the association...
20.
Chen P, Cheng N, Lin C, Chang K, Lu Y, Tsai T, et al.
Clin Nucl Med . 2024 Oct; 50(2):e68-e79. PMID: 39479972
Purpose: This multicenter study investigates the efficacy of 18 F-FDG PET/CT in postradiotherapy (post-RT) response evaluation in salivary gland carcinoma (SGC). Methods: We retrospectively reviewed 115 SGC patients who underwent...