Chi Fung Willis Chow
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Explore the profile of Chi Fung Willis Chow including associated specialties, affiliations and a list of published articles.
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7
Citations
104
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Recent Articles
1.
Chow C, Ghosh S, Hadarovich A, Toth-Petroczy A
Proc Natl Acad Sci U S A
. 2024 Oct;
121(42):e2401622121.
PMID: 39383002
Intrinsically disordered regions (IDRs) are structurally flexible protein segments with regulatory functions in multiple contexts, such as in the assembly of biomolecular condensates. Since IDRs undergo more rapid evolution than...
2.
Rostam N, Ghosh S, Chow C, Hadarovich A, Landerer C, Ghosh R, et al.
Nat Methods
. 2023 Apr;
20(5):673-676.
PMID: 37024650
The discovery of biomolecular condensates transformed our understanding of intracellular compartmentalization of molecules. To integrate interdisciplinary scientific knowledge about the function and composition of biomolecular condensates, we developed the crowdsourcing...
3.
Zhai L, Huang C, Ning Z, Zhang Y, Zhuang M, Yang W, et al.
Cell Host Microbe
. 2022 Dec;
31(1):33-44.e5.
PMID: 36495868
Diarrhea-predominant irritable bowel syndrome (IBS-D), a globally prevalent functional gastrointestinal (GI) disorder, is associated with elevated serotonin that increases gut motility. While anecdotal evidence suggests that the gut microbiota contributes...
4.
Guo X, Asthana P, Gurung S, Zhang S, Wong S, Fallah S, et al.
Nat Commun
. 2022 Jun;
13(1):3749.
PMID: 35768470
Insulin sensitivity progressively declines with age. Currently, the mechanism underlying age-associated insulin resistance remains unknown. Here, we identify membrane-bound matrix metalloproteinase 14 (MT1-MMP/MMP14) as a central regulator of insulin sensitivity...
5.
Chow C, Guo X, Asthana P, Zhang S, Wong S, Fallah S, et al.
Nat Metab
. 2022 Feb;
4(2):203-212.
PMID: 35177851
GDNF-family receptor a-like (GFRAL) has been identified as the cognate receptor of growth/differentiation factor 15 (GDF15/MIC-1), considered a key signaling axis in energy homeostasis and body weight regulation. Currently, little...
6.
Chow C, Che S, Qin H, Kwan H, Bian Z, Wong H
Cell Cycle
. 2019 Jul;
18(16):1824-1829.
PMID: 31272268
Environmental stressors in early childhood can have a detrimental impact later in life, manifesting in functional gastrointestinal disorders including irritable bowel syndrome (IBS). The phenomenon is also observed in rodents,...
7.
Wong H, Qin H, Tsang S, Zuo X, Che S, Chow C, et al.
Nat Commun
. 2019 Apr;
10(1):1745.
PMID: 30988299
Early childhood is a critical period for development, and early life stress may increase the risk of gastrointestinal diseases including irritable bowel syndrome (IBS). In rodents, neonatal maternal separation (NMS)...