Chi-Chao Chan
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Explore the profile of Chi-Chao Chan including associated specialties, affiliations and a list of published articles.
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336
Citations
10525
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Recent Articles
1.
Hu D, Zhang R, Iacob C, Yao A, Yang S, Chan C, et al.
Exp Eye Res
. 2025 Mar;
254:110318.
PMID: 40032151
Constitutive secretion of VEGF is crucial for maintaining ocular circulation while hypoxia-induced VEGF secretion plays an important role in pathological neovascularization. Previous studies have highlighted the critical function of RPE...
2.
3.
Lee H, Xu B, Lewkowicz A, Engel K, Kelley-Baker L, McWilliams I, et al.
EBioMedicine
. 2024 Jun;
104:105170.
PMID: 38823088
Background: Ebola virus disease (EVD) survivors experience ocular sequelae including retinal lesions, cataracts, and vision loss. While monoclonal antibodies targeting the Ebola virus glycoprotein (EBOV-GP) have shown promise in improving...
4.
Deng Y, Ge X, Li Y, Zou B, Wen X, Chen W, et al.
Cell Discov
. 2024 May;
10(1):51.
PMID: 38750045
No abstract available.
5.
Hu D, Zhang R, Iacob C, Yao S, Yang S, Chan C, et al.
Exp Eye Res
. 2023 Dec;
239:109749.
PMID: 38113956
Pam3CSK4 activates Toll-like receptors 2 and 1 (TLR1/2), which recognize mainly molecules from gram-positive pathogens. The effect of Pam3CSK4 on various cytokine and chemokine expression in cultured human uveal melanocytes...
6.
Sen H, Vannella K, Wang Y, Chung J, Kodati S, Ramelli S, et al.
Am J Pathol
. 2023 Mar;
193(11):1809-1816.
PMID: 36963628
Ophthalmic manifestations and tissue tropism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported in association with coronavirus disease 2019 (COVID-19), but the pathology and cellular localization of...
7.
Chen S, Popp N, Chan C
Expert Rev Ophthalmol
. 2022 May;
9(4):285-295.
PMID: 35600070
Age-related macular degeneration (AMD) is a leading cause of blindness in people over the age of 55. Despite its common nature, the etiology of the disease involves both genetic and...
8.
Jiao X, Ma Z, Lei J, Liu P, Cai X, Shahi P, et al.
Front Cell Dev Biol
. 2022 Jan;
9:810020.
PMID: 35096838
We constructed and characterized knockout and conditional knockout mice for KCNJ13, encoding the inwardly rectifying K channel of the Kir superfamily Kir7.1, mutations in which cause both Snowflake Vitreoretinal Degeneration...
9.
Hu D, Zhang R, Iacob C, Yao S, Yang S, Chan C, et al.
Exp Eye Res
. 2022 Jan;
216:108943.
PMID: 35074346
Fibroblast-stimulating lipopeptide (FSL-1) can activate Toll-like receptor 2 and 6 (TLR2/6), which recognize relevant molecules from gram-positive pathogens, fungus, and mycoplasma, and elevates the expression of CXCL1 and CXCL2, neutrophil...
10.
Lal T, Yu Z, Guan B, Bender C, Chan C, Cukras C, et al.
JAMA Ophthalmol
. 2021 Aug;
139(9):1029-1032.
PMID: 34351381
Importance: Asymmetric retinitis pigmentosa (RP) is a rare presentation of a normally symmetric condition. Histopathologic evidence should be examined to see if this asymmetry extends to the tissue and cellular...