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Cheol-Hun Son

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Articles 16
Citations 229
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Recent Articles
1.
Lee Y, Heo W, Son C, Kang C, Park Y, Bae J
Mol Med Rep . 2019 Aug; 20(4):3301-3307. PMID: 31432134
c‑Myc is a characteristic oncogene with dual functions in cell proliferation and apoptosis. Since the overexpression of the c‑Myc proto‑oncogene is a common event in the development and growth of...
2.
Choi C, Jeong M, Park Y, Son C, Lee H, Koh E
Cancer Res Treat . 2018 Jun; 51(2):464-473. PMID: 29879758
Purpose: The purpose of this study was to investigate the efficacy of stereotactic body radiation therapy (SBRT) as a tumor-associated antigen (TAA) presentation method for dendritic cell (DC) sensitization and...
3.
Lee H, Son C, Koh E, Bae J, Kang C, Yang K, et al.
Sci Rep . 2017 Sep; 7(1):11075. PMID: 28894091
Natural killer (NK) cells are considered a promising strategy for cancer treatment. Various methods for large-scale NK cell expansion have been developed, but they should guarantee that no viable cells...
4.
Son C, Bae J, Lee H, Yang K, Park Y
Oncol Lett . 2017 May; 13(5):3781-3786. PMID: 28521478
Cytotoxic T lymphocyte antigen-4 (CTLA-4) is expressed during cluster of differentiation (CD)4+ T-cell activation and terminates immune responses by interrupting CD28-enhanced activation. In addition, CTLA-4 is known to be constitutively...
5.
Son C, Lee H, Koh E, Shin D, Bae J, Yang K, et al.
Sci Rep . 2016 Sep; 6:32470. PMID: 27671170
Decitabine has been found to have anti-metabolic and anti-tumor activities in various tumor cells. Recently, the use of decitabine in combination with other conventional therapies reportedly resulted in improved anti-tumor...
6.
Son C, Bae J, Shin D, Lee H, Jo W, Yang K, et al.
Int J Radiat Oncol Biol Phys . 2015 Mar; 92(2):390-8. PMID: 25754628
Purpose: To investigate the potential of low-dose cyclophosphamide (LD-CTX) and anti-CD25 antibody to prevent activation of regulatory T cells (Tregs) during radiation therapy. Methods And Materials: We used LD-CTX and...
7.
Son C, Bae J, Lee H, Shin D, Yang K, Park Y
J Immunother . 2015 Mar; 38(3):107-15. PMID: 25751500
Regulatory T cells (Tregs) is one of the main obstacles to the success of cancer immunotherapy. The effect of dendritic cell (DC)-based immunotherapy can be attenuated by immune suppressive functions...
8.
Kim S, Ha G, Bae J, Kim G, Son C, Park Y, et al.
Exp Cell Res . 2014 Sep; 330(2):451-459. PMID: 25218028
In the present study, we investigated whether celecoxib could induce the expression of NKG2D ligands in clonogenic colon cancer cells, and increase their susceptibility to NK cell-mediated cell death. Celecoxib...
9.
Son C, Bae J, Shin D, Lee H, Yang K, Park Y
Immunol Invest . 2014 Mar; 43(5):447-62. PMID: 24654594
Various ex vivo or in vivo loading protocols have been developed or evaluated for the delivery of tumor antigens to dendritic cells (DCs). We compared the antitumor effect of mature...
10.
Son C, Keum J, Yang K, Nam J, Kim M, Kim S, et al.
Radiat Oncol . 2014 Feb; 9:49. PMID: 24512718
Background: The overexpression of histone deacetylase (HDAC) and a subsequent decrease in the acetylation levels of nuclear histones are frequently observed in cancer cells. Generally it was accepted that the...