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Chenrui Xu

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Articles 5
Citations 134
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Recent Articles
1.
Wang N, Sun C, Ju Y, Huang L, Liu Y, Gu M, et al.
Exp Eye Res . 2024 Feb; 240:109825. PMID: 38360087
The cause of Posner-Schlossman syndrome (PSS) remains unknown and its frequent recurrence may eventually lead to irreversible damage of the optic nerve. The influence of immune factors in the pathophysiology...
2.
Yu D, Song W, Tan E, Liu L, Cao Y, Jirschitzka J, et al.
Cell . 2022 May; 185(13):2370-2386.e18. PMID: 35597242
2',3'-cAMP is a positional isomer of the well-established second messenger 3',5'-cAMP, but little is known about the biology of this noncanonical cyclic nucleotide monophosphate (cNMP). Toll/interleukin-1 receptor (TIR) domains of...
3.
Stsiapanava A, Xu C, Nishio S, Han L, Yamakawa N, Carroni M, et al.
Nat Struct Mol Biol . 2022 Mar; 29(3):190-193. PMID: 35273390
Glycoprotein 2 (GP2) and uromodulin (UMOD) filaments protect against gastrointestinal and urinary tract infections by acting as decoys for bacterial fimbrial lectin FimH. By combining AlphaFold2 predictions with X-ray crystallography...
4.
Gong Q, Robinson K, Xu C, Huynh P, Chong K, Tan E, et al.
Nat Commun . 2021 Jan; 12(1):188. PMID: 33420028
Nod-like receptor (NLR) proteins activate pyroptotic cell death and IL-1 driven inflammation by assembling and activating the inflammasome complex. Closely related sensor proteins NLRP1 and CARD8 undergo unique auto-proteolysis-dependent activation...
5.
Stsiapanava A, Xu C, Brunati M, Zamora-Caballero S, Schaeffer C, Bokhove M, et al.
EMBO J . 2020 Nov; 39(24):e106807. PMID: 33196145
Assembly of extracellular filaments and matrices mediating fundamental biological processes such as morphogenesis, hearing, fertilization, and antibacterial defense is driven by a ubiquitous polymerization module known as zona pellucida (ZP)...