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Cheng-Zhi Chai

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Articles 15
Citations 91
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Recent Articles
1.
Xiao N, Qian Y, Chai C
Zhongguo Zhong Yao Za Zhi . 2024 Jul; 49(12):3288-3294. PMID: 39041091
This study aimed to explore the regulating effect of Gegen Decoction(GGD) on the hypothalamic-pituitary-ovarian axis(HPOA) dysfunction in the mouse model of primary dysmenorrhea(PD). The mouse model of PD with periodic...
2.
Zhou S, Fan K, Gu L, Yu B, Chai C
Chin J Nat Med . 2022 May; 20(5):321-331. PMID: 35551768
Abelmoschus manihot (L.) Medik. (A. manihot) is a traditional Chinese herbal medicine with a variety of pharmacological properties. It was first recorded in Jiayou Materia Medica dating back to the...
3.
Hong F, Yan Y, Zhao L, Yu B, Chai C
Zhongguo Zhong Yao Za Zhi . 2021 Dec; 46(22):5944-5952. PMID: 34951186
This study analyzed the plasma components of Gegen Decoction(GGD) by ultra-high-performance liquid chromatography-quadrupole-time of flight mass spectrometry(UHPLC-Q-TOF-MS), which is expected to serve as a reference for exploring the pharmacodynamic substances...
4.
He G, Duan Y, Hong F, Yu B, Chai C
Zhongguo Zhong Yao Za Zhi . 2021 Sep; 46(15):3926-3933. PMID: 34472269
This study aimed to explore the characteristic role of Puerariae Lobatae Radix(PLR) in Gegen Decoction for the treatment of primary dysmenorrhea(PD). Estrogen(E_2) was combined with oxytocin to establish a mouse...
5.
Gu L, Ge H, Zhao L, Wang Y, Zhang F, Tang H, et al.
Front Pharmacol . 2020 Jul; 11:996. PMID: 32719603
Renal fibrosis is the final common pathological manifestation of almost all progressive chronic kidney diseases (CKD). Transient receptor potential canonical (TRPC) channels, especially TRPC3/6, were proposed to be essential therapeutic...
6.
Liu Z, Chai C
Zhongguo Zhong Yao Za Zhi . 2019 Dec; 44(18):3883-3889. PMID: 31872719
Ephedra is a classic herb in traditional Chinese medicine( TCM). The new effects of ephedra were gradually found,and the contraindications of the drug were broken in later ages. Because the...
7.
Gong P, He Y, Qi J, Chai C, Yu B
J Ethnopharmacol . 2019 Sep; 246:112209. PMID: 31479708
Ethnopharmacological Relevance: Radix Scrophulariae (RS), is a renowned traditional Chinese medicine used as nourishing 'Yin'. The iridoid glycosides (IG) and phenylpropanoid glycosides (PG) are main chemical constituents in RS. However,...
8.
Chai C, Yu B
Zhongguo Zhong Yao Za Zhi . 2018 Jun; 43(12):2460-2464. PMID: 29950060
Many classical prescriptions still have superior clinical values nowadays, and their modern studies also have far-reaching scientific research demonstration values. Gegen decoction, a representative prescription for common cold due to...
9.
Yang L, Chai C, Yan Y, Duan Y, Henz A, Zhang B, et al.
Molecules . 2017 Aug; 22(9). PMID: 28850076
Licorice derived from the roots and rhizomes of . (Fabaceae), is one of the most widely-used traditional herbal medicines in China. It has been reported to possess significant analgesic activity...
10.
Chai C, Mo W, Zhuang X, Kou J, Yan Y, Yu B
Evid Based Complement Alternat Med . 2016 Apr; 2016:4682786. PMID: 27073402
Right ventricular (RV) dysfunction and failure contribute to the increasing morbidity and mortality of cardiovascular diseases; however, current treatment strategies are grossly inadequate. Sheng-Mai-San (SMS) has been used to treat...