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Chen-Zhong Li

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Articles 128
Citations 1058
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Recent Articles
1.
Yu J, Zhou R, Liu S, Zheng J, Yan H, Su S, et al.
Anal Chem . 2025 Mar; PMID: 40057850
Early and precise diagnosis of neurodegenerative disorders like Alzheimer's (AD) and Parkinson's (PD) is crucial for slowing their progression and enhancing patient outcomes. Exosomal microRNAs (miRNAs) are emerging as promising...
2.
Yan S, Zhang W, Li X, Dutta S, Castle A, Liu Y, et al.
Cell Rep Med . 2025 Mar; :101999. PMID: 40056910
Accurate diagnosis of early Parkinson's disease requires platforms suitable for detecting minute amounts of neuronally derived biomarkers in the massive protein excess of easily accessible biofluids such as blood. Here,...
3.
Liu S, Li Y, Yang Y, Li X, Wang L, Xiao X, et al.
Biosens Bioelectron . 2025 Jan; 272():117058. PMID: 39746282
This review examines the potential of aggregation-induced luminescence (AIE) materials in lateral flow assays (LFA) to enhance the sensitivity and specificity of a range of assay applications. LFA is a...
4.
Lu Y, Liu C, Liu Y, Gu H, Luo X, Jiang C, et al.
Biosens Bioelectron . 2024 Dec; 272():117065. PMID: 39740589
Conventional fluorescent probes with weak fluorescence signals and aggregation-caused quenching effect limits in biomarkers detection, thus requiring many labeled target molecules to combine their output to achieve higher signal-to noise....
5.
Wang J, Zhou Q, Zhang Y, Zhao S, Li L, Zeng Z, et al.
Small . 2024 Nov; 21(2):e2407685. PMID: 39564758
Viruses can infiltrate the central nervous system and contribute to depression, which may include alterations in dopamine (DA) metabolism triggered by immune responses though the specific mechanisms involved remain unclear....
6.
Ge Q, Han Q, Han Y, Ma F, Li C, Zhang C
Chem Commun (Camb) . 2023 Dec; 60(4):408-411. PMID: 38084051
We construct a single quantum dot-based nanosensor for piRNA detection based on ligation-mediated multi-cycle signal amplification. This nanosensor is homogenous, selective, and sensitive with a detection limit of 0.104 fM....
7.
Hu J, Zhang Y, Han Y, Ma F, Li C, Cui L, et al.
Anal Chem . 2023 Nov; 95(48):17945-17953. PMID: 38000786
-Methyladenosine (mA) is the most pervasive and evolutionarily conserved epitranscriptomic modification in long noncoding RNA (lncRNA), and its dysregulation may induce aberrant transcription and translation programs. Herein, we demonstrate the...
8.
Zeng Z, Wang J, Zhao S, Zhang Y, Fan J, Wu H, et al.
Adv Sci (Weinh) . 2023 Nov; 10(36):e2304079. PMID: 37943018
Malignant tumors pose a serious risk to human health. Ascorbic acid (AA) has potential for tumor therapy; however, the mechanism underlying the ability of AA to selectively kill tumor cells...
9.
Subramanian N, Watson B, Li C, Moss M, Liu C
Sens Actuators Rep . 2023 Sep; 6. PMID: 37663321
Aggregation of amyloid-β peptide (Aβ) is hypothesized to be the primary cause of Alzheimer's disease (AD) progression. Aβ aggregation has been widely studied using conventional sensing tools like emission fluorescence,...
10.
Zhang X, Yang Q, Ma L, Zhang D, Lin W, Schlensky N, et al.
Biosens Bioelectron . 2023 Aug; 239:115626. PMID: 37643493
It is difficult to show microbial growth kinetics online when they grow in complex matrices. We presented a novel strategy to address this challenge by developing a high-performance microbial growth...