Chen-Hsiung Yeh
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Explore the profile of Chen-Hsiung Yeh including associated specialties, affiliations and a list of published articles.
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16
Citations
156
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Recent Articles
1.
Lee T, Kantarjian H, Ma W, Yeh C, Giles F, Albitar M
PLoS One
. 2011 Aug;
6(8):e23396.
PMID: 21858098
Background: Mutations in the thrombopoietin receptor (MPL) may activate relevant pathways and lead to chronic myeloproliferative neoplasms (MPNs). The mechanisms of MPL activation remain elusive because of a lack of...
2.
Donahue A, Abdool A, Gaur R, Wohlgemuth J, Yeh C
Leuk Res
. 2011 Jul;
35(11):1477-83.
PMID: 21764131
Current strategies for detecting chromosome abnormalities in MDS/AML include FISH or traditional cytogenetics. MLPA detects abnormalities in multiple loci simultaneously, with higher resolution and throughput. Peripheral blood from 50 healthy...
3.
Yeh C, Abdool A, Bruey J
Cancer Biomark
. 2011 Jun;
7(6):295-303.
PMID: 21694468
In targeted therapy using tyrosine kinase inhibitors (TKIs), measurement of TK activities could be beneficial for diagnosis, identification of potential responders, and monitoring treatment efficacy. Here we evaluated the utility...
4.
Ma W, Zhang X, Wang X, Zhang Z, Yeh C, Uyeji J, et al.
Diagn Mol Pathol
. 2011 Feb;
20(1):34-9.
PMID: 21326037
Mutations in the thrombopoietin receptor gene (myeloproliferative leukemia, MPL) have been reported in patients with JAK2 V617F-negative chronic myeloproliferative disorders (MPDs). We evaluated the prevalence of MPL mutations relative to...
5.
Ma W, Kantarjian H, Zhang K, Zhang X, Wang X, Chen C, et al.
BMC Med Genet
. 2010 Nov;
11:163.
PMID: 21078205
Background: Myelodysplastic syndrome (MDS) may be induced by certain mutagenic environmental or chemotherapeutic toxins; however, the role of susceptibility genes remains unclear. The G/G genotype of the single-nucleotide polymorphism (SNP)...
6.
Abdool A, Donahue A, Wohlgemuth J, Yeh C
PLoS One
. 2010 Nov;
5(10):e15407.
PMID: 21049055
Current diagnostic screening strategies based on karyotyping or fluorescent in situ hybridization (FISH) for detection of chromosomal abnormalities in chronic lymphocytic leukemia (CLL) are laborious, time-consuming, costly, and have limitations...
7.
Ma W, Kantarjian H, Zhang X, Wang X, Zhang Z, Yeh C, et al.
PLoS One
. 2010 Aug;
5(8):e12165.
PMID: 20730051
Background: The JAK2 V617F mutation in exon 14 is the most common mutation in chronic myeloproliferative neoplasms (MPNs); deletion of the entire exon 14 is rarely detected. In our previous...
8.
Chang R, Yeh C, Albitar M
Curr Drug Targets
. 2010 Apr;
11(8):994-9.
PMID: 20426764
Here we review phospho-specific, quantitative flow cytometry approach as a rapid and reliable tool for measuring intracellular signaling proteins with potential applications in monitoring efficacy of targeted therapy. The single...
9.
Abdool A, Yeh C, Kantarjian H, OBrien S, Bruey J, Giles F, et al.
Exp Hematol
. 2010 Apr;
38(6):462-71.
PMID: 20362641
Objective: CD33 is a cell surface antigen for committed myelomonocytic lineage. We explored the potential of detecting CD33 as cell-free circulating protein in patients with leukemia. Materials And Methods: We...
10.
Yeh C, Tseng R, Hannah A, Estrov Z, Estey E, Kantarjian H, et al.
Leuk Res
. 2009 Oct;
34(5):605-9.
PMID: 19800118
The heat shock protein 70 (HSP70) is one of the molecular chaperone family involved in the protection of cells upon exposure to various types of stresses. Plasma circulating HSP70 (cHSP70)...