Chen-Chuan Cheng
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Explore the profile of Chen-Chuan Cheng including associated specialties, affiliations and a list of published articles.
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42
Citations
462
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Recent Articles
1.
Hung Y, Cheng C, Lu Y, Huang S, Chen Y, Lin F, et al.
Cardiovasc Toxicol
. 2025 Jan;
25(3):471-485.
PMID: 39838186
Ventricular arrhythmias (VAs) are major causes of sudden cardiac death in chronic kidney disease (CKD) patients. Indoxyl sulfate (IS) is one common uremic toxin found in CKD patients. This study...
2.
Lu Y, Cheng C, Chen Y, Lin Y, Higa S, Kao Y, et al.
Fundam Clin Pharmacol
. 2023 Sep;
38(2):262-275.
PMID: 37664898
Background: Metabolic stress predisposes to ventricular arrhythmias and sudden cardiac death. Right ventricular outflow tract (RVOT) is the common origin of ventricular arrhythmias. Adenosine monophosphate-regulated protein kinase (AMPK) activation is...
3.
Lu Y, Cheng C, Huang S, Chen Y, Kao Y, Lin Y, et al.
Front Cardiovasc Med
. 2022 Feb;
8:813589.
PMID: 35118146
Rationale: Atrial fibrillation is a critical health burden. Targeting calcium (Ca) dysregulation and oxidative stress are potential upstream therapeutic strategies. Fibroblast growth factor (FGF) 1 can modulate Ca homeostasis and...
4.
Chang J, Cheng C, Lu Y, Chung C, Yeh Y, Chen Y, et al.
Eur J Pharmacol
. 2021 Oct;
911:174547.
PMID: 34624234
Atrial fibrillation (AF) is a common form of arrhythmia with serious public health impacts, but its underlying mechanisms are not yet fully understood. Vascular endothelial growth factor (VEGF) is highly...
5.
Chang J, Cheng C, Lu Y, Chen Y, Chen S, Chen Y
Iran J Basic Med Sci
. 2020 Aug;
23(7):865-870.
PMID: 32774807
Objectives: Drug-induced atrial fibrillation (AF) is considered an adverse effect of chemotherapeutic drugs. AF is a crucial risk factor for stroke, heart failure, myocardial infarction, and mortality. Pulmonary veins (PVs)...
6.
Lin Y, Cheng C, Huang J, Chen Y, Lu Y, Chen Y, et al.
Exp Ther Med
. 2020 Apr;
19(4):2773-2782.
PMID: 32256760
Phosphodiesterase (PDE)3-5 are expressed in cardiac tissue and play critical roles in the pathogenesis of heart failure and atrial fibrillation. PDE inhibitors are widely used in the clinic, but their...
7.
Lu Y, Cheng C, Wu H, Lin Y, Chen Y, Chen S, et al.
Clin Exp Pharmacol Physiol
. 2019 Oct;
47(2):247-254.
PMID: 31637746
Atrial fibrillation (AF) is the most common form of arrhythmia and increases the risk of stroke and heart failure (HF). Pulmonary veins (PVs) are important sources of triggers that generate...
8.
Chang C, Cheng C, Chen Y, Higa S, Huang J, Chen S, et al.
Eur J Pharmacol
. 2018 Jul;
833:462-471.
PMID: 30017860
Factor Xa inhibitors reduce stroke in patients with atrial fibrillation. Pulmonary veins (PVs) and the sinoatrial node (SAN) are crucial for genesis of atrial fibrillation. However, the electrophysiological effects of...
9.
Lu Y, Wu W, Lin Y, Cheng C, Chen Y, Chen S, et al.
Eur J Clin Invest
. 2017 Nov;
48(1).
PMID: 29130489
Background: Atrial fibrillation (AF) is the most common sustained arrhythmia, and pulmonary veins (PVs) play a critical role in triggering AF. Angiotensin (Ang)-(1-7) regulates calcium (Ca ) homoeostasis and also...
10.
Lin Y, Cheng C, Tsai M, Wu P, Chen Y, Chen Y, et al.
Exp Ther Med
. 2017 Jun;
13(5):2486-2492.
PMID: 28565869
Atrial fibrillation (AF) is associated with mitochondrial dysfunction. Sinoatrial node (SAN) dysfunction increases arrhythmogenesis of pulmonary veins (PVs), which is the most important trigger of AF; however, it is not...