Che-Fan Huang
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Explore the profile of Che-Fan Huang including associated specialties, affiliations and a list of published articles.
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13
Citations
32
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Recent Articles
1.
Le P, Quinn J, Flozak A, Steffeck A, Huang C, Gottardi C
Biol Open
. 2025 Jan;
14(1.
PMID: 39782767
Epithelial cell cohesion and barrier function critically depend on α-catenin, an actin-binding protein and essential constituent of cadherin-catenin-based adherens junctions. α-catenin undergoes actomyosin force-dependent unfolding of both actin-binding and middle...
2.
Zou Y, Huang C, Sturrock G, Kelleher N, Fitzgerald M
Anal Chem
. 2024 Nov;
96(49):19597-19604.
PMID: 39602376
The crucial roles of proteoforms in biological processes and disease mechanisms have been increasingly recognized. However, the rate at which new proteoforms are being discovered using top-down proteomics has far...
3.
Forte E, Sanders J, Pla I, Kanchustambham V, Hollas M, Huang C, et al.
Mol Cell Proteomics
. 2024 Nov;
23(12):100876.
PMID: 39521382
Cirrhosis, advanced liver disease, affects 2 to 5 million Americans. While most patients have compensated cirrhosis and may be fairly asymptomatic, many decompensate and experience life-threatening complications such as gastrointestinal...
4.
Huang C, Hollas M, Sanchez A, Bhattacharya M, Ho G, Sundaresan A, et al.
J Proteome Res
. 2024 Sep;
23(10):4694-4703.
PMID: 39312774
The dynamic range challenge for the detection of proteins and their proteoforms in human plasma has been well documented. Here, we use the nanoparticle protein corona approach to enrich low-abundance...
5.
Le P, Quinn J, Flozak A, Steffeck A, Huang C, Gottardi C
bioRxiv
. 2024 Sep;
PMID: 39282345
Epithelial cell cohesion and barrier function critically depend on -catenin, an actin-binding protein and essential constituent of cadherin-catenin-based adherens junctions. -catenin undergoes actomyosin force-dependent unfolding of both actin-binding and middle...
6.
Huang C, Hollas M, Sanchez A, Bhattacharya M, Ho G, Sundaresan A, et al.
bioRxiv
. 2024 Jul;
PMID: 39071411
The dynamic range challenge for detection of proteins and their proteoforms in human plasma has been well documented. Here, we use the nanoparticle protein corona approach to enrich low-abundant proteins...
7.
Huang C, Su P, Fisher T, Levitsky J, Kelleher N, Forte E
Front Transplant
. 2024 Jul;
2():1286881.
PMID: 38993855
Scarcity of high-quality organs, suboptimal organ quality assessment, unsatisfactory pre-implantation procedures, and poor long-term organ and patient survival are the main challenges currently faced by the solid organ transplant (SOT)...
8.
Forte E, Sanders J, Pla I, Kanchustambham V, Hollas M, Huang C, et al.
bioRxiv
. 2024 Jul;
PMID: 38948836
Cirrhosis, advanced liver disease, affects 2-5 million Americans. While most patients have compensated cirrhosis and may be fairly asymptomatic, many decompensate and experience life-threatening complications such as gastrointestinal bleeding, confusion...
9.
Huang C, Kline J, Negrao F, Robey M, Toby T, Durbin K, et al.
Anal Chem
. 2024 Feb;
96(8):3578-3586.
PMID: 38354049
Existing mass spectrometric assays used for sensitive and specific measurements of target proteins across multiple samples, such as selected/multiple reaction monitoring (SRM/MRM) or parallel reaction monitoring (PRM), are peptide-based methods...
10.
Huang C, Gottardi C, Mrksich M
Sci Rep
. 2022 Sep;
12(1):15095.
PMID: 36064958
Phosphorylation controls important cellular signals and its dysregulation leads to disease. While most phospho-regulation studies are focused on kinases, phosphatases are comparatively overlooked. Combining peptide arrays with SAMDI mass spectrometry,...