Charlotte K Callaghan
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Explore the profile of Charlotte K Callaghan including associated specialties, affiliations and a list of published articles.
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12
Citations
129
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Recent Articles
1.
Callaghan C, Rouine J, OMara S
Prog Brain Res
. 2018 Oct;
239:89-119.
PMID: 30314570
Deficits in motivation are at the core of many neuropsychiatric disorders, including major depressive disorder (MDD). Research in MDD has been heavily focused on anhedonia and depression or negative/positive symptoms...
2.
Rouine J, Callaghan C, OMara S
Prog Brain Res
. 2018 Oct;
239:229-252.
PMID: 30314568
Depression is the leading cause of disability worldwide, with over 300 million people affected. Almost all currently available antidepressant treatments target monoamine neurotransmitter systems and have a delayed onset of...
3.
Barlow S, Fahey B, Smith K, Passecker J, Della-Chiesa A, Hok V, et al.
Brain Res Bull
. 2018 May;
140:212-219.
PMID: 29782908
Patients receiving cytokine immunotherapy with IFN-α frequently present with neuropsychiatric consequences and cognitive impairments, including a profound depressive-like symptomatology. While the neurobiological substrates of the dysfunction that leads to adverse...
4.
Callaghan C, Rouine J, Dean R, Knapp B, Bidlack J, Deaver D, et al.
Brain Behav Immun
. 2017 Aug;
67:152-162.
PMID: 28844812
Patients receiving the cytokine immunotherapy, interferon-alpha (IFN-α) frequently present with neuropsychiatric consequences and cognitive impairments. Patients (25-80%) report symptoms of depression, including, anhedonia, irritability, fatigue and impaired motivation. Our lab...
5.
Callaghan C, Rouine J, OMara S
Physiol Behav
. 2017 Jul;
179:377-383.
PMID: 28711394
Aerobic exercise has marked effects on mood and cognition. Here, we used an interferon-alpha (IFN-α) induced depression model to evaluate the potential efficacy of chronic treadmill running on mood and...
6.
Rahman M, Callaghan C, Kerskens C, Chattarji S, OMara S
Sci Rep
. 2016 Jul;
6:29127.
PMID: 27374165
Exposure to severe and prolonged stress has detrimental effects on the hippocampus. However, relatively little is known about the gradual changes in hippocampal structure, and its behavioral consequences, over the...
7.
Callaghan C, OMara S
Behav Brain Res
. 2015 May;
290:84-9.
PMID: 25940764
Clinical studies report evidence of long-term cognitive and other deficits following adjunctive chemotherapy treatment, which is often termed "chemobrain" or "chemo-fog". The neurological bases of these impairments are poorly understood....
8.
Callaghan C, Kelly A
Neurobiol Learn Mem
. 2013 May;
104:39-48.
PMID: 23669064
The neurotrophin family of proteins are believed to mediate various forms of synaptic plasticity in the adult brain. Here we have assessed the roles of these proteins in object recognition...
9.
Callaghan C, Hok V, Della-Chiesa A, Virley D, Upton N, OMara S
Neuropharmacology
. 2012 Jul;
63(5):890-7.
PMID: 22766392
Alterations in synaptic plasticity and neurocognitive function with age have been well documented in the literature. These changes are accompanied by modifications of neurotransmitter systems in the central nervous system...
10.
Callaghan C, Kelly A
Hippocampus
. 2012 May;
22(11):2127-35.
PMID: 22573708
Consolidation of long-term memory is dependent on synthesis of new proteins in the hippocampus and associated cortical regions. The neurotrophin brain-derived neurotrophic factor (BDNF) is tightly regulated by activity-dependent cellular...