Charley C Gruber
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Explore the profile of Charley C Gruber including associated specialties, affiliations and a list of published articles.
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9
Citations
301
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Recent Articles
1.
Gruber C, Babu V, Livingston K, Joisher H, Walker G
mBio
. 2022 Feb;
13(1):e0375621.
PMID: 35130721
Various lethal stresses, including bactericidal antibiotics, can trigger the production of reactive oxygen species (ROS) that contribute to killing. Incomplete base excision repair (BER) of oxidized nucleotides, especially 8-oxo-dG, has...
2.
Gruber C, Walker G
DNA Repair (Amst)
. 2018 Sep;
71:108-117.
PMID: 30181041
Numerous lethal stresses in bacteria including antibiotics, thymineless death, and MalE-LacZ expression trigger an increase in the production of reactive oxygen species. This results in the oxidation of the nucleotide...
3.
Cameron E, Gruber C, Ritchie J, Waldor M, Sperandio V
Infect Immun
. 2018 Jan;
86(4).
PMID: 29358334
The QseEF histidine kinase/response regulator system modulates expression of enterohemorrhagic (EHEC) and serovar Typhimurium virulence genes in response to the host neurotransmitters epinephrine and norepinephrine. , which encodes an outer...
4.
Takahashi N, Gruber C, Yang J, Liu X, Braff D, Yashaswini C, et al.
Proc Natl Acad Sci U S A
. 2017 Aug;
114(34):9164-9169.
PMID: 28794281
Downstream metabolic events can contribute to the lethality of drugs or agents that interact with a primary cellular target. In bacteria, the production of reactive oxygen species (ROS) has been...
5.
Ghosal A, Kohrer C, Babu V, Yamanaka K, Davies B, Jacob A, et al.
Biochem Biophys Res Commun
. 2017 Feb;
484(3):612-617.
PMID: 28153719
The product of the human C21orf57 (huYBEY) gene is predicted to be a homologue of the highly conserved YbeY proteins found in nearly all bacteria. We show that, like its...
6.
Gruber C, Sperandio V
Infect Immun
. 2015 Jan;
83(4):1286-95.
PMID: 25605763
Enterohemorrhagic Escherichia coli (EHEC) is a significant human pathogen and is the cause of bloody diarrhea and hemolytic-uremic syndrome. The virulence repertoire of EHEC includes the genes within the locus...
7.
Gruber C, Sperandio V
mBio
. 2014 Jan;
5(1):e01025-13.
PMID: 24425733
Unlabelled: Remodeling of the host cytoskeleton is a common strategy employed by bacterial pathogens. Although there is vigorous investigation of the cell biology underlying these bacterially mediated cytoskeleton modifications, knowledge...
8.
Kendall M, Gruber C, Parker C, Sperandio V
mBio
. 2012 May;
3(3).
PMID: 22589288
Unlabelled: Bacterial pathogens must be able to both recognize suitable niches within the host for colonization and successfully compete with commensal flora for nutrients in order to establish infection. Ethanolamine...
9.
Kendall M, Gruber C, Rasko D, Hughes D, Sperandio V
J Bacteriol
. 2011 Oct;
193(24):6843-51.
PMID: 21984790
Enterohemorrhagic Escherichia coli O157:H7 (EHEC) causes bloody diarrhea and hemolytic-uremic syndrome. EHEC encodes the sRNA chaperone Hfq, which is important in posttranscriptional regulation. In EHEC strain EDL933, Hfq acts as...