Charles Winterhalter
Overview
Explore the profile of Charles Winterhalter including associated specialties, affiliations and a list of published articles.
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7
Citations
54
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Recent Articles
1.
Pelliciari S, Bodet-Lefevre S, Fenyk S, Stevens D, Winterhalter C, Schramm F, et al.
Nat Commun
. 2023 Dec;
14(1):8339.
PMID: 38097584
Genome duplication is essential for the proliferation of cellular life and this process is generally initiated by dedicated replication proteins at chromosome origins. In bacteria, DNA replication is initiated by...
2.
Winterhalter C, Pelliciari S, Stevens D, Fenyk S, Marchand E, Cronin N, et al.
Nucleic Acids Res
. 2023 Apr;
51(9):4322-4340.
PMID: 37093985
Genome replication is a fundamental biological activity shared by all organisms. Chromosomal replication proceeds bidirectionally from origins, requiring the loading of two helicases, one for each replisome. However, the molecular...
3.
Winterhalter C, Stevens D, Fenyk S, Pelliciari S, Marchand E, Soultanas P, et al.
Nucleic Acids Res
. 2022 Nov;
51(9):4302-4321.
PMID: 36416272
Bidirectional DNA replication from a chromosome origin requires the asymmetric loading of two helicases, one for each replisome. Our understanding of the molecular mechanisms underpinning helicase loading at bacterial chromosome...
4.
Gaimster H, Winterhalter C, Koh A, Murray H
Methods Mol Biol
. 2022 May;
2476:263-276.
PMID: 35635709
Research over the last two decades has revealed that bacterial genomes are highly organized and that bacteria have sophisticated mechanisms in place to ensure their correct replication and segregation into...
5.
Tellechea-Luzardo J, Winterhalter C, Widera P, Kozyra J, de Lorenzo V, Krasnogor N
ACS Synth Biol
. 2020 Feb;
9(3):536-545.
PMID: 32078768
As DNA sequencing and synthesis become cheaper and more easily accessible, the scale and complexity of biological engineering projects is set to grow. Yet, although there is an accelerating convergence...
6.
Martin E, Williams H, Pitoulias M, Stevens D, Winterhalter C, D Craggs T, et al.
Nucleic Acids Res
. 2018 Dec;
47(4):2101-2112.
PMID: 30534966
The homotetrameric DnaD protein is essential in low G+C content gram positive bacteria and is involved in replication initiation at oriC and re-start of collapsed replication forks. It interacts with...
7.
Winterhalter C, Widera P, Krasnogor N
Bioinformatics
. 2013 Dec;
30(7):1029-30.
PMID: 24363376
Summary: JEPETTO (Java Enrichment of Pathways Extended To TOpology) is a Cytoscape 3.x plugin performing integrative human gene set analysis. It identifies functional associations between genes and known cellular pathways,...