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Charles McSharry

Explore the profile of Charles McSharry including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
11.
Hasan S, Jozwik A, Heaps A, Kakkar N, Donnelly I, Cookson S, et al.
Allergy . 2019 Dec; 75(6):1469-1473. PMID: 31833564
No abstract available.
12.
Yang J, Chaudhuri R, Thomson N, Ramparsad N, OPray H, Barclay S, et al.
NPJ Prim Care Respir Med . 2018 Sep; 28(1):35. PMID: 30232329
The United Kingdom National Review of Asthma Deaths (NRAD) recommends that patients who require ≥3 courses of oral corticosteroids (OCS) for exacerbations in the past year or those on British...
13.
Alivernini S, Gremese E, McSharry C, Tolusso B, Ferraccioli G, McInnes I, et al.
Front Immunol . 2018 Jan; 8:1932. PMID: 29354135
MicroRNAs (miRNAs) are small non-coding RNAs that fine-tune the cell response to a changing environment by modulating the cell transcriptome. miR-155 is a multifunctional miRNA enriched in cells of the...
14.
Kurowska-Stolarska M, Alivernini S, Melchor E, Elmesmari A, Tolusso B, Tange C, et al.
Nat Commun . 2017 Jun; 8:15877. PMID: 28639625
Current treatments for rheumatoid arthritis (RA) do not reverse underlying aberrant immune function. A genetic predisposition to RA, such as HLA-DR4 positivity, indicates that dendritic cells (DC) are of crucial...
15.
Skaaby T, Taylor A, Jacobsen R, Paternoster L, Thuesen B, Ahluwalia T, et al.
Sci Rep . 2017 May; 7(1):2224. PMID: 28533558
Observational studies on smoking and risk of hay fever and asthma have shown inconsistent results. However, observational studies may be biased by confounding and reverse causation. Mendelian randomization uses genetic...
16.
Kurowska-Stolarska M, Hasoo M, Welsh D, Stewart L, McIntyre D, Morton B, et al.
J Allergy Clin Immunol . 2016 Oct; 139(6):1946-1956. PMID: 27746237
Background: Idiopathic pulmonary fibrosis (IPF) is progressive and rapidly fatal. Improved understanding of pathogenesis is required to prosper novel therapeutics. Epigenetic changes contribute to IPF; therefore, microRNAs may reveal novel...
17.
Chaudhuri R, McSharry C, Heaney L, Niven R, Brightling C, Menzies-Gow A, et al.
Respir Med . 2016 Sep; 118:46-52. PMID: 27578470
Background: Asthma in the elderly as well as asthma of adult-onset has been associated with increased morbidity, but little is known specifically about the effects of age on clinical and...
18.
Elmesmari A, Fraser A, Wood C, Gilchrist D, Vaughan D, Stewart L, et al.
Rheumatology (Oxford) . 2016 Jul; 55(11):2056-2065. PMID: 27411480
Objective: To test the hypothesis that miR-155 regulates monocyte migratory potential via modulation of chemokine and chemokine receptor expression in RA, and thereby is associated with disease activity. Methods: The...
19.
Chaudhuri R, McSharry C, Spears M, Brady J, Grierson C, Messow C, et al.
Transl Respir Med . 2016 May; 1(1):11. PMID: 27234393
Background: Matrix-metalloproteinase (MMP)-9 has been implicated in the pathogenesis of COPD, although its link to disease severity is unclear. The purpose of the study was to examine the relationship between...
20.
McSharry C, Johnstone S
Pol Arch Med Wewn . 2016 Mar; 126(3):118-20. PMID: 27026095
No abstract available.