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Charles L Wiseman

Explore the profile of Charles L Wiseman including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 165
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Recent Articles
1.
Wiseman C, Holmes J, Calfa C, Dakhil S, Bhattacharya S, Peoples G, et al.
Hum Vaccin Immunother . 2024 Aug; 20(1):2379864. PMID: 39165083
This Phase I/IIa open-label, single-arm clinical trial addressing advanced, refractory, metastatic breast cancer was conducted at six medical centers in the United States. We repeated inoculations with irradiated SV-BR-1-GM, a...
2.
Wiseman C, Kharazi A, Sunkari V, Galeas J, Dozio V, Hashwah H, et al.
Recent Pat Anticancer Drug Discov . 2022 May; 18(2):224-240. PMID: 35593340
Background: SV-BR-1-GM, derived from a patient with grade 2 (moderately differentiated) breast cancer, is a GM-CSF-secreting breast cancer cell line with properties of antigen-presenting cells. SV-BR-1-GM and next-generation versions are...
3.
Lacher M, Bauer G, Fury B, Graeve S, Fledderman E, Petrie T, et al.
Front Immunol . 2018 Jun; 9:776. PMID: 29867922
Targeted cancer immunotherapy with irradiated, granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting, allogeneic cancer cell lines has been an effective approach to reduce tumor burden in several patients. It is generally assumed that...
4.
Wiseman C, Kharazi A
Breast J . 2006 Sep; 12(5):475-80. PMID: 16958969
A patient with recurrent breast cancer metastases following initial response to chemotherapy and hormonal maintenance was treated with a whole-cell tumor vaccine, resulting in a prompt objective complete remission of...
5.
de Pillis L, Radunskaya A, Wiseman C
Cancer Res . 2005 Sep; 65(17):7950-8. PMID: 16140967
Mathematical models of tumor-immune interactions provide an analytic framework in which to address specific questions about tumor-immune dynamics. We present a new mathematical model that describes tumor-immune interactions, focusing on...
6.
Kudinov Y, Wiseman C, Kharazi A
Cancer Cell Int . 2003 Jun; 3:4. PMID: 12787470
Background: The expression of major histocompatibility complex class II (MHCII) antigens in both mouse and human tumors is rare, and these antigens are not easily inducible by IFN-gamma (IFNg). Since...