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Charles Hillier

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Articles 11
Citations 838
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Recent Articles
1.
Blackstone J, Williams T, Nicholas J, Bordea E, De Angelis F, Bianchi A, et al.
BMJ Open . 2024 Sep; 14(9):e086414. PMID: 39284697
Introduction: There remains a high unmet need for disease-modifying therapies that can impact disability progression in secondary progressive multiple sclerosis (SPMS). Following positive results of the phase 2 MS-STAT study,...
2.
Singh T, Hinton J, Swallow R, Kersey J, Hillier C
Echo Res Pract . 2020 Jul; 7(3):K17-K20. PMID: 32698155
Young stroke patients should be investigated thoroughly to look for cardiac and extra-cardiac sources of emboli. We present a patient who was investigated for a cardiac source of emboli following...
3.
Hillier C, Pardo M, Yu L, Bushell E, Sanderson T, Metcalf T, et al.
Cell Rep . 2019 Aug; 28(6):1635-1647.e5. PMID: 31390575
Malaria represents a major global health issue, and the identification of new intervention targets remains an urgent priority. This search is hampered by more than one-third of the genes of...
4.
Thomas S, Fazakarley L, Thomas P, Collyer S, Brenton S, Perring S, et al.
BMJ Open . 2017 Sep; 7(9):e016966. PMID: 28954791
Objectives: While the health and well-being benefits of physical activity are recognised, people with multiple sclerosis (MS) often face greater barriers than the general population. The Nintendo Wii potentially offers...
5.
George J, Leite M, Kitley J, Jones N, Cortes N, Donati M, et al.
JAMA Neurol . 2014 Sep; 71(11):1429-32. PMID: 25199567
Importance: Patients with neuromyelitis optica who have aquaporin-4 antibodies are being identified and receiving immunosuppressant treatment earlier and more aggressively as a result of increasing awareness of the importance of...
6.
Thomas P, Thomas S, Kersten P, Jones R, Slingsby V, Nock A, et al.
BMC Neurol . 2014 Jun; 14:109. PMID: 24886398
Background: Fatigue is one of the most common and debilitating symptoms of multiple sclerosis (MS). The aim was to evaluate the effectiveness at 1-year follow-up of a manualised group-based programme...
7.
Thomas S, Fazakarley L, Thomas P, Brenton S, Collyer S, Perring S, et al.
BMJ Open . 2014 May; 4(5):e005172. PMID: 24812193
Introduction: The benefits of physical activity for people with multiple sclerosis (pwMS) have been recognised. However, exercise regimens can be difficult to maintain over the longer term and pwMS may...
8.
Beecham A, Patsopoulos N, Xifara D, Davis M, Kemppinen A, Cotsapas C, et al.
Nat Genet . 2013 Oct; 45(11):1353-60. PMID: 24076602
Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 potentially associated regions (P < 1.0...
9.
Thomas S, Thomas P, Kersten P, Jones R, Green C, Nock A, et al.
J Neurol Neurosurg Psychiatry . 2013 May; 84(10):1092-9. PMID: 23695501
Background: Fatigue is a common and troubling symptom for people with multiple sclerosis (MS). Aim: To evaluate the effectiveness and cost-effectiveness of a six-session group-based programme for managing MS-fatigue (Fatigue:...
10.
Thomas P, Thomas S, Kersten P, Jones R, Nock A, Slingsby V, et al.
BMC Neurol . 2010 Jun; 10:43. PMID: 20553617
Background: Fatigue is one of the most commonly reported and debilitating symptoms of multiple sclerosis (MS); approximately two-thirds of people with MS consider it to be one of their three...