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Charles C Valentine

Explore the profile of Charles C Valentine including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 57
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Recent Articles
1.
LeBlanc D, Zhou G, Williams A, Meier M, Valentine C, Salk J, et al.
Biol Reprod . 2025 Feb; PMID: 39936590
Germ cell mutagenicity testing is increasingly required for chemical risk assessment. Duplex Sequencing (DS) is rapidly gaining acceptance as a method to assess in vivo mutagenesis, and as a valid...
2.
Serrano I, Hirose M, Valentine C, Roesner S, Schmidt E, Pratt G, et al.
Nat Ecol Evol . 2025 Jan; PMID: 39885344
No abstract available.
3.
Serrano I, Hirose M, Valentine C, Roesner S, Schmidt E, Pratt G, et al.
Nat Ecol Evol . 2024 Feb; 8(5):1021-1034. PMID: 38361161
Mitochondrial genomes co-evolve with the nuclear genome over evolutionary timescales and are shaped by selection in the female germline. Here we investigate how mismatching between nuclear and mitochondrial ancestry impacts...
4.
Lynch A, Zanoni T, Salk J, Martincorena I, Young R, Kucab J, et al.
Mutagenesis . 2023 Jun; 38(4):192-200. PMID: 37300447
The use of error-corrected Next Generation Sequencing (ecNG) to determine mutagenicity has been a subject of growing interest and potentially a disruptive technology that could supplement, and in time, replace...
5.
Serrano I, Hirose M, Valentine C, Roesner S, Schmidt E, Pratt G, et al.
bioRxiv . 2023 Mar; PMID: 36945529
Mitochondrial genomes co-evolve with the nuclear genome over evolutionary timescales and are shaped by selection in the female germline. Here, we investigate how mismatching between nuclear and mitochondrial ancestry impacts...
6.
Wang Y, Mittelstaedt R, Wynne R, Chen Y, Cao X, Muskhelishvili L, et al.
Environ Mol Mutagen . 2021 May; 62(5):306-318. PMID: 34050964
The organotypic human air-liquid-interface (ALI) airway tissue model has been used as an in vitro cell culture system for evaluating the toxicity of inhaled substances. ALI airway cultures are highly...
7.
Salk J, Loubet-Senear K, Maritschnegg E, Valentine C, Williams L, Higgins J, et al.
Cell Rep . 2019 Jul; 28(1):132-144.e3. PMID: 31269435
High-accuracy next-generation DNA sequencing promises a paradigm shift in early cancer detection by enabling the identification of mutant cancer molecules in minimally invasive body fluid samples. We demonstrate 80% sensitivity...