Chaohong Wu
Overview
Explore the profile of Chaohong Wu including associated specialties, affiliations and a list of published articles.
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4
Citations
78
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Recent Articles
1.
Schulte J, Sepp K, Wu C, Hong P, Littleton J
PLoS One
. 2011 Sep;
6(8):e23841.
PMID: 21909362
To identify Huntington's Disease therapeutics, we conducted high-content small molecule and RNAi suppressor screens using a Drosophila primary neural culture Huntingtin model. Drosophila primary neurons offer a sensitive readout for...
2.
Wu C, Schulte J, Sepp K, Littleton J, Hong P
Neuroinformatics
. 2010 Apr;
8(2):83-100.
PMID: 20405243
Cell-based high content screening (HCS) is becoming an important and increasingly favored approach in therapeutic drug discovery and functional genomics. In HCS, changes in cellular morphology and biomarker distributions provide...
3.
Schulte J, Sepp K, Jorquera R, Wu C, Song Y, Hong P, et al.
J Neurosci
. 2010 Apr;
30(15):5189-203.
PMID: 20392941
The monopolar spindle-one-binder (Mob) family of kinase-interacting proteins regulate cell cycle and cell morphology, and their dysfunction has been linked to cancer. Models for Mob function are primarily based on...
4.
Schoemans R, Aigrot M, Wu C, Maree R, Hong P, Belachew S, et al.
J Inherit Metab Dis
. 2010 Feb;
33(2):113-20.
PMID: 20151197
Phenylketonuria (PKU) is a metabolic genetic disease characterized by deficient phenylalanine hydroxylase (PAH) enzymatic activity. Brain hypomyelination has been reported in untreated patients, but its mechanism remains unclear. We therefore...