Chao-Lin Lu
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Explore the profile of Chao-Lin Lu including associated specialties, affiliations and a list of published articles.
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12
Citations
123
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Recent Articles
1.
Yang Y, Lu C, Lo S, Peng C, Liu Y
Med Hypotheses
. 2015 Jun;
85(3):367-70.
PMID: 26048359
Schizophrenia is a major mental disorder in which patients' cognitive functions gradually deteriorate. Pharmacological intervention with antipsychotics has proven effective, yet it is still debatable whether to initiate treatment in...
2.
Li J, Lu C, Cheng M, Luu S, Hsu S, Hu T, et al.
PLoS One
. 2014 Jan;
9(1):e85373.
PMID: 24416398
Aberrant synaptic dysfunction is implicated in the pathogenesis of schizophrenia. The DLGAP2 gene encoding the SAP90/PSD-95-associated protein 2 (SAPAP2) located at the post-synaptic density of neuronal cells is involved in...
3.
Lu C, Ku Y, Lo S, Peng C, Tung C, Lin Y, et al.
Neurosci Lett
. 2013 Oct;
556:210-5.
PMID: 24135334
Serotonin (5-HT)-related drugs are extensively employed in the treatment of mental disorders. However, the roles of the central serotonergic system in impulse control over environmental stimuli remain to be elucidated....
4.
Li J, Lu C, Cheng M, Luu S, Hsu S, Chen C
Psychiatry Res
. 2013 Feb;
208(1):84-7.
PMID: 23414653
We resequenced the exonic regions of the DLGAP3 gene, which encodes SAP90/PSD95-associated protein 3, in 215 schizophrenic patients and 215 non-psychotic controls. Seven known single-nucleotide polymorphisms (SNPs) were identified, but...
5.
Li J, Lu C, Cheng M, Luu S, Hsu S, Chen C
Psychiatry Res
. 2012 Sep;
205(1-2):13-7.
PMID: 22940546
Schizophrenia is a severe chronic mental disorder with high genetic components in its etiology. Several studies indicated that synaptic dysfunction is involved in the pathophysiology of schizophrenia. Postsynaptic synapse-associated protein...
6.
Chang Y, Tao S, Lu C
Int J Ment Health Nurs
. 2012 Aug;
22(3):272-8.
PMID: 22882876
Medication non-adherence is associated with higher rates of relapse in persons with schizophrenia. Psychiatric nurses play a significant role in facilitating their medication adherence. The motivators which strengthen patients with...
7.
Cheng M, Chuang Y, Lu C, Chen Y, Luu S, Li J, et al.
Prog Neuropsychopharmacol Biol Psychiatry
. 2012 Jun;
39(1):149-55.
PMID: 22691714
Objective: Early growth response genes (EGR1, 2, 3, and 4) encode a family of nuclear proteins that function as transcriptional regulators. They are involved in the regulation of synaptic plasticity,...
8.
Cheng M, Lu C, Luu S, Tsai H, Hsu S, Chen T, et al.
PLoS One
. 2010 Dec;
5(12):e15107.
PMID: 21151988
Hypofunction of N-methyl-D-aspartate (NMDA) receptor-mediated signal transduction has been implicated in the pathophysiology of schizophrenia. Post-synaptic density protein 95 (PSD95) plays a critical role in regulating the trafficking and activity...
9.
Lu C, Wang Y, Chen J, Lai I, Liou Y
Neurosci Lett
. 2010 Jul;
481(2):120-5.
PMID: 20600594
Cellular, animal and human studies support the involvement of aberrant NRG-ErbB signaling in the pathogenesis of schizophrenia. The aim of the present study was to examine whether genetic variation in...
10.
Shen Y, Liao D, Lu C, Chen J, Liou Y, Chen T, et al.
Schizophr Res
. 2010 Jun;
121(1-3):179-86.
PMID: 20541370
Objectives: Vesicular glutamate transporters (VGLUT1-3) package glutamate into vesicles in the presynaptic terminal and regulate the release of glutamate. In mesencephalic dopamine neuron culture, the majority of isolated dopamine neurons...