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Chao-Jin Xu

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Articles 18
Citations 145
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Recent Articles
1.
Wang J, Xu Z, Zhan L, Liao M, Xu C
Anal Biochem . 2023 May; 672:115179. PMID: 37150424
The development of heat-induced antigen retrieval technologies with Tris-EDTA buffer has dramatically improved immunostaining of specific antigens for routine immunohistochemical detection (Krenacs et al., 2010) [1]. However, little evidence exists...
2.
Zhang C, Li Q, Zhan L, Wang X, Zhang J, Xu C
Anal Biochem . 2023 Feb; 665:115070. PMID: 36736988
Inactivation of horseradish peroxidase (HRP) treatment is a conventional preference to stripping for sequential detections of different proteins of chemiluminescent western blotting (WB). However, little evidence exists on whether other...
3.
Wang J, Li M, Zhang J, Xu C
Biotech Histochem . 2021 Dec; 97(6):404-414. PMID: 34903132
For western blot analysis, a housekeeping protein, such as β-actin or glyceraldehyde-3-phosphate dehydrogenase, is used as loading control with the assumption that these proteins are stable. In practice, these internal...
4.
Xu C, Li M, Li-Zhao , Chen W, Wang J
Aging (Albany NY) . 2021 Oct; 13(19):23133-23148. PMID: 34620734
High-fat diet (HFD) has been associated with neuroinflammation and apoptosis in distinct brain regions. To explore the effect of short-term (7, 14 and 21 days) high-fat overfeeding on apoptosis, inflammatory...
5.
Wang J, Chen W, Zhang J, Xu C
J Mol Histol . 2021 Feb; 52(3):521-537. PMID: 33555537
Nogo-A protein consists of two main extracellular domains: Nogo-66 (rat amino acid [aa] 1019-1083) and Nogo-A-Δ20 (extracellular, active 180 amino acid Nogo-A region), which serve as strong inhibitors of axon...
6.
Wang J, Zhao L, Li M, Chen W, Xu C
Anal Biochem . 2020 Jan; 592:113579. PMID: 31926891
A modified, sensitive and reversible method for protein staining on nitrocellulose (NC) and polyvinylidine fluoride (PVDF) membranes was developed in Western blotting. The method employed Congo red staining to visualize...
7.
Wang J, Xu C
Biomed Pharmacother . 2019 Dec; 122:109691. PMID: 31786465
Astrocytes can serve multiple functions in maintaining cellular homeostasis of the central nervous system (CNS), and normal functions for autophagy in astrocytes is considered to have very vital roles in...
8.
Xu C, Wang J, Jing-Pan , Min-Liao
Curr Alzheimer Res . 2019 Mar; 16(3):219-232. PMID: 30827242
Background: Amyloid-β (Aβ) accumulation plays a critical role in the pathogenesis of Alzheimer's disease (AD) lesions. Deficiency of Serotonin signaling recently has been linked to the increased Aβ level in...
9.
Wang J, Wang J, Cai Z, Xu C
Int J Mol Med . 2018 Sep; 42(5):2481-2488. PMID: 30226560
Curcumin is an orange-yellow colored, lipophilic polyphenol substance derived from the rhizome of Curcuma longa that is widely used in many countries. Curcumin has many reported functions, including antioxidant and...
10.
Zhang C, Wu J, Liao M, Wang J, Xu C
J Mol Neurosci . 2016 Aug; 60(4):474-485. PMID: 27541019
Simvastatin, a lipophilic and fermentation-derived natural statin, is reported to treat neurological disorders, such as traumatic brain injury, Parkinson's disease (PD), Alzheimer disease (AD), etc. Recently, research also indicated that...