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Changqin Gu

Explore the profile of Changqin Gu including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 188
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Recent Articles
1.
Chen C, Li M, Guo A, Guo P, Zhang W, Gu C, et al.
NPJ Vaccines . 2025 Feb; 10(1):32. PMID: 39955275
Influenza virus nucleoprotein (NP) is a promising target for universal influenza vaccines due to its conservation and high immunogenicity. Here, we uncovered a previously unknown factor that E. coli-produced NP...
2.
Sun X, Jin X, Lin Z, Liu X, Yang J, Li L, et al.
Vet Res . 2024 Dec; 55(1):161. PMID: 39696641
The primary cause of viral encephalitis (VE) is invasion of the central nervous system (CNS) by the virus, which leads to neuroinflammation and poses a significant threat to global public...
3.
Wu S, Gou F, Meng J, Jin X, Liu W, Ding W, et al.
Vet Microbiol . 2024 May; 293:110100. PMID: 38718527
Recent epidemiological studies have discovered that a lot of cases of porcine epidemic diarrhea virus (PEDV) infection are frequently accompanied by porcine kobuvirus (PKV) infection, suggesting a potential relationship between...
4.
Li M, Chen C, Wang X, Guo P, Feng H, Zhang X, et al.
Antiviral Res . 2023 Jul; 217:105688. PMID: 37516153
Vaccines that trigger mucosal immune responses at the entry portals of pathogens are highly desired. Here, we showed that antigen-decorated nanoparticle generated through CRISPR engineering of T4 bacteriophage can serve...
5.
Sun X, Jin X, Liu X, Wang L, Li L, Yang J, et al.
Virol J . 2023 Jul; 20(1):151. PMID: 37452371
Pseudorabies virus (PRV) can infect multiple hosts and lead to fatal encephalitis. There is a significant increase in the number of microglia in the brain of animals infected with PRV....
6.
Su N, Lin Z, Liu X, Sun X, Jin X, Feng H, et al.
Vet Res Commun . 2023 Jun; 47(4):1949-1962. PMID: 37266866
The thymus, the central immune organ in mammals, plays an important role in immune defense. Porcine reproductive and respiratory syndrome virus (PRRSV) infection in piglets can cause thymus injury and...
7.
Gao M, Liu Z, Guo X, Zhang J, Cheng G, Hu X, et al.
Arch Virol . 2023 May; 168(6):169. PMID: 37233865
Japanese encephalitis virus (JEV) infection can cause brain tissue lesions characterized by neuronal death, and apoptosis is involved in JEV-induced neuronopathy. In the present study, mouse microglia were infected with...
8.
Zhao Z, Li Q, Ashraf U, Yang M, Zhu W, Gu J, et al.
Elife . 2022 Aug; 11. PMID: 35972780
Zika virus (ZIKV) can be transmitted from mother to fetus during pregnancy, causing adverse fetal outcomes. Several studies have indicated that ZIKV can damage the fetal brain directly; however, whether...
9.
Zhang J, Han W, Xie C, Gao M, Wang X, Hu X, et al.
Arch Virol . 2022 Feb; 167(3):849-859. PMID: 35119507
Japanese encephalitis (JE) is a zoonotic epidemic disease caused by Japanese encephalitis virus (JEV), and currently, no medicines are available to treat this disease. Autophagy modulators play an important role...
10.
Li M, Guo P, Chen C, Feng H, Zhang W, Gu C, et al.
Front Immunol . 2021 Oct; 12():745625. PMID: 34712234
Developing influenza vaccines that protect against a broad range of viruses is a global health priority. Several conserved viral proteins or domains have been identified as promising targets for such...