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Chang-Nim Im

Explore the profile of Chang-Nim Im including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 287
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Recent Articles
1.
Kim K, Kim S, Im C, Na K, Lee M, Park J, et al.
Biochem Biophys Res Commun . 2023 Jan; 647:30-36. PMID: 36709670
Tumor priming is considered a promising strategy for improving drug distribution in malignant tissues. Multicellular layers (MCLs) of human cancer cells are potentially useful models for evaluating tumor-priming agents. We...
2.
Jang S, Song J, Kim H, Im C, Khawar I, Park J, et al.
Cancers (Basel) . 2021 Dec; 13(23). PMID: 34885065
Activated pancreatic stellate cells (aPSCs) and M2 macrophages modulate tumor progression and therapeutic efficacy in pancreatic ductal adenocarcinoma (PDAC) via epithelial-mesenchymal transition (EMT). Here, our aim was to analyze the...
3.
Choi M, Jin Y, Kim H, Chai Y, Im C, Lee S, et al.
Basic Clin Pharmacol Toxicol . 2021 Jan; 128(5):686-698. PMID: 33404192
Cocaine and heroin cause impairment of neural plasticity in the brain including striatum. This study aimed to identify genes differentially expressed in the striatum of cynomolgus monkeys in response to...
4.
Choi M, Jin Y, Bang S, Im C, Lee Y, Kim H, et al.
Clin Psychopharmacol Neurosci . 2020 Jan; 18(1):93-108. PMID: 31958910
Objective: The aim of this study was to investigate differentially expressed genes and their functions in the hippocampus and striatum after heroin administration in cynomolgus macaques of different ages. Methods:...
5.
Park S, Hong M, Lee H, Ye B, Hwang S, Jung S, et al.
J Gastroenterol Hepatol . 2019 May; 34(12):2118-2125. PMID: 31039275
Background And Aim: Anti-tumor necrosis factor (TNF) agents, such as infliximab (IFX), have been increasingly used to induce and maintain disease remission in patients with Crohn's disease (CD). Despite a...
6.
Im C
Biomed Res Int . 2017 Jun; 2017:5832824. PMID: 28642874
PPAR is a nuclear receptor that regulates differentiation and proliferation and is highly expressed in many cancer cells. Its synthetic ligands, such as rosiglitazone and ciglitazone, and its inhibitor GW9662,...
7.
Lee J, Kim Y, Im C, Kim S, Kim S, Min S, et al.
J Agric Food Chem . 2017 May; 65(22):4472-4483. PMID: 28502165
Airway epithelial cells are often infected by respiratory syncytial virus (RSV), one of the most common causes of asthma, bronchiolitis, chronic obstructive pulmonary disease, and pneumonia. During the infection process,...
8.
Im C, Yun H, Lee J
Int J Mol Sci . 2017 Mar; 18(2). PMID: 28241425
Heat shock factor 1 (HSF1), a transcription factor activated by various stressors, regulates proliferation and apoptosis by inducing expression of target genes, such as heat shock proteins and Bcl-2 (B-cell...
9.
Seo S, Lee J, Yun H, Im C, Kim Y, Ko J, et al.
Mol Neurobiol . 2017 Jan; 55(2):1259-1270. PMID: 28116547
The induction of senescence in cancer cells has recently been implicated as a mechanism of tumor regression in response to various modes of stress. 14-3-3 proteins are conserved scaffolding molecules...
10.
Yun Kim H, Kim Y, Yun H, Im C, Ko J, Lee J
Exp Mol Med . 2016 Sep; 48(9):e260. PMID: 27659916
B-cell lymphoma (BCL)-2-interacting cell death suppressor (BIS) has diverse cellular functions depending on its binding partners. However, little is known about the effects of biochemical modification of BIS on its...