Chandrashekhar D Patil
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Explore the profile of Chandrashekhar D Patil including associated specialties, affiliations and a list of published articles.
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47
Citations
642
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Recent Articles
1.
Borase H, Patil C, Valyi-Nagy T, Shukla D
mBio
. 2025 Feb;
:e0376524.
PMID: 40013778
Importance: Herpes simplex virus-1 (HSV-1) infection in the brain can lead to severe and often permanent neurological consequences. Host factors influence disease outcomes in response to infection, and understanding these...
2.
Patil C, Borase H, Gagan S, Sharma P, Kapoor D, Yadavalli T, et al.
Invest Ophthalmol Vis Sci
. 2024 Jun;
65(6):36.
PMID: 38916883
Purpose: Neutrophils are known mediators of innate immunity, yet their effector function in herpesvirus infections remains poorly understood. Here, we elucidate the mechanistic action and pivotal role of neutrophil extracellular...
3.
Suryawanshi R, Patil C, Agelidis A, Koganti R, Yadavalli T, Ames J, et al.
Sci Adv
. 2023 Apr;
9(17):eadf3977.
PMID: 37115924
Limited knowledge exists on exogenous DNA virus reinfections. Herpes simplex virus-1 (HSV-1), a prototype DNA virus, causes multiple human diseases including vision-threatening eye infections. While reinfection with an exogenous HSV-1...
4.
Suryawanshi R, Patil C, Wu D, Panda P, Singh S, Volety I, et al.
Antiviral Res
. 2022 Nov;
208:105454.
PMID: 36334637
Herpes simplex virus type-1 (HSV1) exploits cellular machinery for its own replicative advantage. Current treatment modalities against HSV1 cause toxicity and drug resistance issues. In the search for alternative forms...
5.
Koganti R, Patil C, Shukla D
Trends Microbiol
. 2022 Oct;
30(12):1128-1130.
PMID: 36272886
In a recent article, Gao et al. diversify our knowledge of prokaryotic innate immunity by characterizing a novel bacterial defense system that utilizes nucleotide-binding oligomerization-like receptors (NLRs) for recognizing phage...
6.
Patil C, Suryawanshi R, Kapoor D, Shukla D
mBio
. 2022 Aug;
13(5):e0219422.
PMID: 36043789
Herpes simplex virus type-1 (HSV-1) infections are known to alter the host metabolism for efficient propagation . However, metabolic perturbations upon prolonged HSV-1 infection remain poorly understood. We used high-resolution...
7.
Patil C, Shukla D
Autophagy
. 2022 Feb;
18(4):944-945.
PMID: 35167411
Very little is known about the mechanisms that restrict neurotropic herpesviruses such as herpes simplex virus-1 (HSV-1) from infecting the central nervous system (CNS) and causing widespread death of neurons....
8.
Patil C, Suryawanshi R, Ames J, Koganti R, Agelidis A, Kapoor D, et al.
J Immunol
. 2021 Dec;
208(1):63-73.
PMID: 34880107
Very little knowledge exists on virus-specific host cell intrinsic mechanisms that prevent hyperproliferation of primary HSV type 2 (HSV-2) genital infections. In this study, we provide evidence that the Nemo-related...
9.
Koujah L, Madavaraju K, Agelidis A, Patil C, Shukla D
mBio
. 2021 Nov;
12(6):e0279221.
PMID: 34749529
Under pathological conditions like herpes simplex virus 1 (HSV-1) infection, host-pathogen interactions lead to major reconstruction of the host protein network, which contributes to the dysregulation of signaling pathways and...
10.
Suryawanshi R, Patil C, Agelidis A, Koganti R, Ames J, Koujah L, et al.
Nat Commun
. 2021 Oct;
12(1):6020.
PMID: 34650053
Herpes simplex virus type-1 (HSV-1) causes ocular and orofacial infections. In rare cases, HSV-1 can cause encephalitis, which leads to permanent brain injuries, memory loss or even death. Host factors...