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Chandrakant R Kokare

Explore the profile of Chandrakant R Kokare including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 133
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Recent Articles
1.
Bagul U, Khot S, Ashtekar K, Monde A, Kolhe O, Tagalpallewar A, et al.
Int J Pharm . 2024 Jun; 661:124391. PMID: 38936444
The complex structure of the eye poses challenges in delivering drugs effectively, which can be circumvented by employing nanotechnologies. The present study aimed to prepareacetazolamide-loadedleciplex (ACZ - LP) using a...
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Bagul U, Nazirkar M, Mane A, Khot S, Tagalpallewar A, Kokare C
Int J Pharm . 2023 Dec; 650:123746. PMID: 38145779
The intricate structure of the eye poses difficulties in drug targeting, which can be surmounted with the help of nanoformulation strategies. With this view, brinzolamide nanosponges (BNS) were prepared using...
4.
Gadhave D, Sugandhi V, Kokare C
Brain Res . 2023 Nov; 1822:148674. PMID: 37952871
The tight junction of endothelial cells in the central nervous system (CNS) has an ideal characteristic, acting as a biological barrier that can securely regulate the movement of molecules in...
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Kumbhar S, Kokare C, Shrivastava B, Gorain B, Choudhury H
J Pharm Sci . 2021 Jan; 110(4):1761-1778. PMID: 33515583
Delivering therapeutics to the brain using conventional dosage forms is always a challenge, thus the present study was aimed to formulate mucoadhesive nanoemulsion (MNE) of aripiprazole (ARP) for intranasal delivery...
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Kumbhar S, Kokare C, Shrivastava B, Gorain B, Choudhury H
Int J Pharm . 2020 Jun; 586:119499. PMID: 32505580
The tight junctions between capillary endothelial cells of the blood-brain barrier (BBB) restricts the entry of therapeutics into the brain. Potential of the intranasal delivery tool has been explored in...
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Gadhave D, Kokare C
Drug Dev Ind Pharm . 2019 Feb; 45(5):839-851. PMID: 30702966
Background: Multiple sclerosis (MS) is one of the most severe autoimmune disorder of the central nervous system (CNS). Objective: The present research work was aimed to formulate and investigate teriflunomide...
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Asnani G, Kokare C
Biomol Concepts . 2019 Jan; 9(1):190-199. PMID: 30676996
The aim of this study was to formulate a novel dual crosslinked hydrogel bead using Portulaca mucilage for colon-targeted delivery of 5-fluorouracil (5-FU) and evaluate its safety, specificity and efficacy....
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Gadhave D, Tagalpallewar A, Kokare C
AAPS PharmSciTech . 2019 Jan; 20(1):22. PMID: 30604305
Potential risk of agranulocytosis is one of the drug-induced adverse effects of the second-generation antipsychotic agents. The present investigation aimed to formulate and investigate olanzapine (OLZ)-loaded nanostructured lipid carriers (OLZ-NLCs)...
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Barse R, Tagalpallewar A, Kokare C, Sharma J, Sharma P
Drug Dev Ind Pharm . 2017 Dec; 44(5):800-807. PMID: 29228819
Context: Short residence time, poor bioavailability and poor permeability are the major problems for conventional eye drops treatment. Objective: The aim of this article is to develop, optimize and ex...