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Chandra S Boosani

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Articles 31
Citations 2264
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Recent Articles
1.
Baindara P, Roy D, Boosani C, Mandal S, Green J
Appl Environ Microbiol . 2025 Jan; 91(2):e0170224. PMID: 39760495
Antimicrobial peptides (AMPs) have emerged as potential alternatives to conventional antibiotics due to their novelty and multiple mechanisms of action. Because they are peptides, AMPs are amenable to bioengineering and...
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Jiang W, Block M, Boosani C
PLoS One . 2022 Feb; 17(2):e0263190. PMID: 35143520
Vascular restenosis often presents as a consequence of injury to the vessel wall, resulting from stenting and other interventional procedures. Such injury to the arteries induces proliferation of Vascular Smooth...
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Boosani C, Agrawal D
Antibodies (Basel) . 2019 Sep; 5(2). PMID: 31557989
The innate immune response, which is usually referred to as the first line of defense, protects the hosts against pathogenic micro-organisms. Some of the biomolecules released from the pathogens, such...
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Boosani C, Gunasekar P, Agrawal D
Expert Opin Ther Pat . 2019 Sep; 29(11):881-889. PMID: 31530116
: A multitude of cellular and physiological functions have been attributed to the biological activity of PTEN (Phosphatase and tensin homolog) such as inhibiting angiogenesis, promoting apoptosis, preventing cell proliferation,...
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Thankam F, Boosani C, Dilisio M, Agrawal D
Int J Mol Med . 2018 Nov; 43(1):3-14. PMID: 30387824
Cellular inflammation is not just an immediate response following pathogenic infections or resulting from damage due to injury, it is also associated with normal physiological functions, including wound healing and...
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Thankam F, Boosani C, Dilisio M, Gross R, Agrawal D
Mol Cell Biochem . 2018 Oct; 454(1-2):97-109. PMID: 30306456
Fatty infiltration and inflammation delay the healing responses and raise major concerns in the therapeutic management of rotator cuff tendon injuries (RCTI). Our evaluations showed the upregulation of 'metabolic check...
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Gunasekar P, Swier V, Fleegel J, Boosani C, Radwan M, Agrawal D
PLoS One . 2018 Oct; 13(10):e0199411. PMID: 30296271
Vitamin D functions as a potent immunomodulator by interacting with many immune cells however, its role in regulating inflammation in the epicardial adipose tissue (EAT) is unclear. In the EAT...
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Boosani C, Gunasekar P, Block M, Jiang W, Zhang Z, Radwan M, et al.
Can J Physiol Pharmacol . 2018 Aug; 96(10):1030-1039. PMID: 30067080
Increased expression of DNA methyltransferase-1 (DNMT1) associates with the progression of many human diseases. Because DNMT1 induces cell proliferation, drugs that inhibit DNMT1 have been used to treat proliferative diseases....
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Jiang W, Agrawal D, Boosani C
Mol Med Rep . 2018 Jun; 18(2):1215-1224. PMID: 29901135
Histone modifications are the key epigenetic mechanisms that have been identified to regulate gene expression in many human diseases. However, in the early developmental stages, such as in utero and...