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Chamith S Rajapakse

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Articles 104
Citations 1233
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Recent Articles
21.
Guha I, Zhang X, Rajapakse C, Letuchy E, Chang G, Janz K, et al.
JBMR Plus . 2022 Jun; 6(6):e10627. PMID: 35720662
Osteoporosis causes bone fragility and elevates fracture risk. Applications of finite element (FE) analysis (FEA) for assessment of trabecular bone (Tb) microstructural strength at whole-body computed tomography (CT) imaging are...
22.
Nguyen J, Baghdadi S, Pogoriler J, Guariento A, Rajapakse C, Arkader A
Radiographics . 2022 May; 42(4):1196-1213. PMID: 35594197
Osteosarcoma is the most common primary bone sarcoma in children. Imaging plays a pivotal role in diagnostic workup, surgical planning, and follow-up monitoring for possible disease relapse. Survival depends on...
23.
Tong Y, Udupa J, McDonough J, Lott C, Wu C, Rajapakse C, et al.
Proc SPIE Int Soc Opt Eng . 2022 Apr; 11598. PMID: 35465442
Quantitative thoracic dynamic magnetic resonance imaging (QdMRI), a recently developed technique, provides a potential solution for evaluating treatment effects in thoracic insufficiency syndrome (TIS). In this paper, we demonstrate how...
24.
Guha I, Zhang X, Rajapakse C, Chang G, Saha P
Med Phys . 2022 Mar; 49(6):3886-3899. PMID: 35319784
Purpose: Osteoporosis is a bone disease associated with enhanced bone loss, microstructural degeneration, and fracture-risk. Finite element (FE) modeling is used to estimate trabecular bone (Tb) modulus from high-resolution three-dimensional...
25.
Suri A, Jones B, Ng G, Anabaraonye N, Beyrer P, Domi A, et al.
Radiol Artif Intell . 2022 Feb; 4(1):e210015. PMID: 35146432
Purpose: To construct and evaluate the efficacy of a deep learning system to rapidly and automatically locate six vertebral landmarks, which are used to measure vertebral body heights, and to...
26.
Gelston D, Brosler S, Vazquez J, Sorci O, Griffith A, Chatterjee S, et al.
Am J Nucl Med Mol Imaging . 2021 Sep; 11(4):271-279. PMID: 34513280
Purpose: To develop a methodology for the quantification of gastrointestinal (GI) inflammation as indicated by 2-deoxy-2-(F)fluoro-D-glucose (FDG) uptake on positron-emissions tomography/computed tomography (PET/CT) imaging. This is intended to investigate the...
27.
Ruderman I, Rajapakse C, Xu W, Tang S, Robertson P, Toussaint N
Bone Rep . 2021 Sep; 15:101120. PMID: 34485631
Background: Secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD) has a significant effect on bone, affecting both trabecular and cortical compartments. Although parathyroidectomy results in biochemical improvement in...
28.
Whitney D, Caird M, Hurvitz E, Rajapakse C, Fedak Romanowski E
Epilepsia . 2021 Jul; 62(9):2180-2189. PMID: 34250606
Objective: The objective of this study was to determine whether two commonly prescribed antiseizure medications (ASMs), levetiracetam (LEV) and oxcarbazepine (OXC), were associated with an increased risk of fragility fracture...
29.
Park P, Raynor W, Sun Y, Werner T, Rajapakse C, Alavi A
Int J Mol Sci . 2021 Jul; 22(12). PMID: 34204387
In a healthy body, homeostatic actions of osteoclasts and osteoblasts maintain the integrity of the skeletal system. When cellular activities of osteoclasts and osteoblasts become abnormal, pathological bone conditions, such...
30.
Whitney D, Kalia V, Rajapakse C, Fedak Romanowski E, Caird M, Hurvitz E, et al.
Bone . 2021 May; 149:115996. PMID: 33962082
Background: Anti-seizure medication (ASM) is necessary to manage epilepsy and often prescribed to children and adolescents, but can lead to iatrogenic effects, including bone fragility by altering bone metabolism. Disrupting...