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Chak Kwong Cheng

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Articles 26
Citations 385
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Recent Articles
1.
Cheng C, Ye L, Wang Y, Wang Y, Xia Y, Wong S, et al.
J Sport Health Sci . 2025 Jan; 101026. PMID: 39827989
Background: Exercise elicits cardiometabolic benefits, reducing the risks of cardiovascular diseases and type 2 diabetes. This study aimed to investigate the vascular and metabolic effects of gut microbiota from exercise-trained...
2.
Cheng C, Yi M, Wang L, Huang Y
Front Immunol . 2024 Sep; 15:1456244. PMID: 39253076
Inflammatory diseases compromise a clinically common and diverse group of conditions, causing detrimental effects on body functions. Gasdermins (GSDM) are pore-forming proteins, playing pivotal roles in modulating inflammation. Belonging to...
3.
Cheng C, Huang Y
J Mol Cell Cardiol . 2024 Aug; 195:97-102. PMID: 39147197
As the innermost monolayer of the vasculature, endothelial cells (ECs) serve as the interface for multiplex signal transduction. Directly exposed to blood-borne factors, both endogenous and exogenous, ECs actively mediate...
4.
Cheng C, Gao J, Kang L, Huang Y
Aging Dis . 2024 Jul; PMID: 39012675
As a major risk factor for cardiometabolic diseases, aging refers to a gradual decline in physiological function, characterized with 12 conspicuous hallmarks, like telomere attrition, chronic inflammation, and dysbiosis. Common...
5.
He L, Chen Q, Wang L, Pu Y, Huang J, Cheng C, et al.
Redox Biol . 2024 Jun; 74:103229. PMID: 38870781
Background: Nuclear erythroid 2-related factor 2 (Nrf2), a transcription factor, is critically involved in the regulation of oxidative stress and inflammation. However, the role of endothelial Nrf2 in atherogenesis has...
6.
Chen Q, Hao H, Guo Z, Zuo Y, Cheng C, Zhang C, et al.
Life Sci . 2024 May; 349:122723. PMID: 38754816
Endothelial dysfunction is the most common pathological feature of cardiovascular diseases, including diabetes mellitus, hypertension and atherosclerosis. It affects both macro- and micro-vasculatures, causing functional impairment of multiple organs. Pien...
7.
Li S, Li H, Kong H, Wu S, Cheng C, Xu J
Front Endocrinol (Lausanne) . 2023 Dec; 14:1292596. PMID: 38149100
It has been well documented that there is a two-way relationship between diabetes mellitus and periodontitis. Diabetes mellitus represents an established risk factor for chronic periodontitis. Conversely, chronic periodontitis adversely...
8.
Cheng C, Huang Y
Med Rev (2021) . 2023 Oct; 3(3):209-213. PMID: 37789958
Our oral cavity houses various types of microbes including bacteria, protozoa, fungi and viruses, harboring over 700 bacterial species. Oral dysbiosis refers to the imbalance between symbionts and pathobionts in...
9.
Cheng C, Huang Y
Med Rev (2021) . 2023 Sep; 1(1):23-46. PMID: 37724079
Our gut microbiome is constituted by trillions of microorganisms including bacteria, archaea and eukaryotic microbes. Nowadays, gut microbiome has been gradually recognized as a new organ system that systemically and...
10.
Wang Y, Jin M, Cheng C, Li Q
Front Endocrinol (Lausanne) . 2023 Aug; 14:1238927. PMID: 37600689
Diabetic kidney disease (DKD) is a chronic complication of diabetes and the leading cause of end-stage renal disease (ESRD) worldwide. Currently, there are limited therapeutic drugs available for DKD. While...