Cesar Fandos
Overview
Explore the profile of Cesar Fandos including associated specialties, affiliations and a list of published articles.
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15
Citations
641
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0
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Recent Articles
1.
Garnica J, Sole P, Yamanouchi J, Moro J, Mondal D, Fandos C, et al.
Elife
. 2024 Nov;
13.
PMID: 39576679
Chronic antigenic stimulation can trigger the formation of interleukin 10 (IL-10)-producing T-regulatory type 1 (TR1) cells in vivo. We have recently shown that murine T-follicular helper (TFH) cells are precursors...
2.
Sole P, Parras D, Yamanouchi J, Garnica J, Garabatos N, Moro J, et al.
Front Immunol
. 2023 May;
14:1177722.
PMID: 37153608
Systemic delivery of nanoparticles (NPs) coated with mono-specific autoimmune disease-relevant peptide-major histocompatibility complex class II (pMHCII) molecules can resolve organ inflammation in various disease models in a disease-specific manner without...
3.
Sole P, Yamanouchi J, Garnica J, Uddin M, Clarke R, Moro J, et al.
Cell Mol Immunol
. 2023 Mar;
20(5):489-511.
PMID: 36973489
Chronic antigenic stimulation can trigger the differentiation of antigen-experienced CD4 T cells into T regulatory type 1 (TR1) cells, a subset of interleukin-10-producing Treg cells that do not express FOXP3....
4.
Yang Y, Ellestad K, Singha S, Uddin M, Clarke R, Mondal D, et al.
J Control Release
. 2021 Sep;
338:557-570.
PMID: 34474072
Nanoparticles (NPs) coated with autoimmune disease-relevant peptide-major histocompatibility complexes (pMHCs) can blunt autoimmune diseases by re-programming cognate effector T-lymphocytes into disease-suppressing regulatory T-cells, followed by massive expansion. Here, a method...
5.
Serra P, Garabatos N, Singha S, Fandos C, Garnica J, Sole P, et al.
Nat Commun
. 2019 Oct;
10(1):4917.
PMID: 31664029
Assembly of soluble peptide-major histocompatibility complex class II (pMHCII) monomers into multimeric structures enables the detection of antigen-specific CD4 T cells in biological samples and, in some configurations, their reprogramming...
6.
Peptide-MHC-based nanomedicines for autoimmunity function as T-cell receptor microclustering devices
Singha S, Shao K, Yang Y, Clemente-Casares X, Sole P, Clemente A, et al.
Nat Nanotechnol
. 2017 Apr;
12(7):701-710.
PMID: 28436959
We have shown that nanoparticles (NPs) can be used as ligand-multimerization platforms to activate specific cellular receptors in vivo. Nanoparticles coated with autoimmune disease-relevant peptide-major histocompatibility complexes (pMHC) blunted autoimmune...
7.
Ramos-Fernandez E, Tajes M, Ill-Raga G, Vargas L, Busquets-Garcia A, Bosch-Morato M, et al.
Oncotarget
. 2016 Aug;
7(37):58876-58892.
PMID: 27557499
The activation of N-Methyl D-Aspartate Receptor (NMDAR) by glutamate is crucial in the nervous system function, particularly in memory and learning. NMDAR is composed by two GluN1 and two GluN2...
8.
Clemente-Casares X, Blanco J, Ambalavanan P, Yamanouchi J, Singha S, Fandos C, et al.
Nature
. 2016 Feb;
530(7591):434-40.
PMID: 26886799
Regulatory T cells hold promise as targets for therapeutic intervention in autoimmunity, but approaches capable of expanding antigen-specific regulatory T cells in vivo are currently not available. Here we show...
9.
Ill-Raga G, Tajes M, Busquets-Garcia A, Ramos-Fernandez E, Vargas L, Bosch-Morato M, et al.
Antioxid Redox Signal
. 2015 Feb;
22(15):1295-307.
PMID: 25706765
Aims: Hippocampus is the brain center for memory formation, a process that requires synaptogenesis. However, hippocampus is dramatically compromised in Alzheimer's disease due to the accumulation of amyloid β-peptide, whose...
10.
Garabatos N, Blanco J, Fandos C, Lopez E, Santamaria P, Ruiz A, et al.
Monoclon Antib Immunodiagn Immunother
. 2014 Oct;
33(5):305-11.
PMID: 25357997
Expression of transcripts for the homotypic adhesion protein epithelial V-like antigen 1 (EVA1), also known as myelin protein zero like-2 (Mpzl2), is known to be present in thymic stromal cells....