Cedric A J Hutter
Overview
Explore the profile of Cedric A J Hutter including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
384
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Recent Articles
1.
Remm S, De Vecchis D, Schoppe J, Hutter C, Gonda I, Hohl M, et al.
Nat Commun
. 2023 Oct;
14(1):6449.
PMID: 37833269
Mycobacterium tuberculosis is protected from antibiotic therapy by a multi-layered hydrophobic cell envelope. Major facilitator superfamily (MFS) transporter Rv1410 and the periplasmic lipoprotein LprG are involved in transport of triacylglycerides...
2.
Meier G, Thavarasah S, Ehrenbolger K, Hutter C, Hurlimann L, Barandun J, et al.
Nat Chem Biol
. 2022 Nov;
19(4):440-450.
PMID: 36443574
Drug efflux is a common resistance mechanism found in bacteria and cancer cells, but studies providing comprehensive functional insights are scarce. In this study, we performed deep mutational scanning (DMS)...
3.
Li T, Cai H, Yao H, Zhou B, Zhang N, Fentener van Vlissingen M, et al.
Nat Commun
. 2022 Jul;
13(1):4359.
PMID: 35896553
No abstract available.
4.
Walter J, Scherer M, Hutter C, Garaeva A, Zimmermann I, Wyss M, et al.
EMBO Rep
. 2022 Mar;
23(4):e54199.
PMID: 35253970
The ongoing COVID-19 pandemic represents an unprecedented global health crisis. Here, we report the identification of a synthetic nanobody (sybody) pair, Sb#15 and Sb#68, that can bind simultaneously to the...
5.
Barland N, Rueff A, Cebrero G, Hutter C, Seeger M, Veening J, et al.
Sci Adv
. 2022 Mar;
8(9):eabm1122.
PMID: 35235350
Phosphocholine molecules decorating bacterial cell wall teichoic acids and outer-membrane lipopolysaccharide have fundamental roles in adhesion to host cells, immune evasion, and persistence. Bacteria carrying the operon that performs phosphocholine...
6.
Deneka D, Rutz S, Hutter C, Seeger M, Sawicka M, Dutzler R
Nat Commun
. 2021 Sep;
12(1):5435.
PMID: 34521847
Members of the LRRC8 family form heteromeric assemblies, which function as volume-regulated anion channels. These modular proteins consist of a transmembrane pore and cytoplasmic leucine-rich repeat (LRR) domains. Despite their...
7.
Li T, Cai H, Yao H, Zhou B, Zhang N, Fentener van Vlissingen M, et al.
Nat Commun
. 2021 Jul;
12(1):4635.
PMID: 34330908
SARS-CoV-2, the causative agent of COVID-19, features a receptor-binding domain (RBD) for binding to the host cell ACE2 protein. Neutralizing antibodies that block RBD-ACE2 interaction are candidates for the development...
8.
Trinco G, Arkhipova V, Garaeva A, Hutter C, Seeger M, Guskov A, et al.
Commun Biol
. 2021 Jun;
4(1):751.
PMID: 34140623
It is well-established that the secondary active transporters Glt and Glt catalyze coupled uptake of aspartate and three sodium ions, but insight in the kinetic mechanism of transport is fragmentary....
9.
Cai H, Yao H, Li T, Hutter C, Li Y, Tang Y, et al.
Commun Biol
. 2020 Dec;
3(1):753.
PMID: 33303987
Green fluorescent proteins (GFPs) are widely used to monitor membrane protein expression, purification, and stability. An ideal reporter should be stable itself and provide high sensitivity and yield. Here, we...
10.
Arnold F, Weber M, Gonda I, Gallenito M, Adenau S, Egloff P, et al.
Nature
. 2020 Apr;
580(7803):413-417.
PMID: 32296173
Intracellular replication of the deadly pathogen Mycobacterium tuberculosis relies on the production of small organic molecules called siderophores that scavenge iron from host proteins. M. tuberculosis produces two classes of...