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Cecilia Maria Lima da Costa

Explore the profile of Cecilia Maria Lima da Costa including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Aguiar T, Rivas M, Silva E, Pires S, Dangoni G, Macedo T, et al.
Biochem Genet . 2024 Jun; PMID: 38822933
No abstract available.
2.
Aguiar T, Rivas M, Silva E, Pires S, Dangoni G, Macedo T, et al.
Biochem Genet . 2024 Apr; PMID: 38649558
Hepatoblastoma stands as the most prevalent liver cancer in the pediatric population. Characterized by a low mutational burden, chromosomal and epigenetic alterations are key drivers of its tumorigenesis. Transcriptome analysis...
3.
Carvalho N, Santiago K, Maia J, DAlmeida Costa F, Formiga M, de Queiroz Soares D, et al.
J Med Genet . 2023 Aug; 61(1):61-68. PMID: 37536918
Background: Sarcomas are a rare and diverse group of cancers occurring mainly in young individuals for which an underlying germline genetic cause remains unclear in most cases. Methods: Germline DNA...
4.
Tasic L, Avramovic N, Jadranin M, Quintero M, Stanisic D, Martins L, et al.
Biomedicines . 2022 Dec; 10(12). PMID: 36551847
Cancer is one of the leading causes of death in children and adolescents worldwide; among the types of liver cancer, hepatoblastoma (HBL) is the most common in childhood. Although it...
5.
Aguiar T, Teixeira A, Scliar M, Sobral de Barros J, Lemes R, Souza S, et al.
Front Genet . 2022 May; 13:858396. PMID: 35495172
The ultrarare hepatoblastoma (HB) is the most common pediatric liver cancer. HB risk is related to a few rare syndromes, and the molecular bases remain elusive for most cases. We...
6.
Rivas M, Aguiar T, Maschietto M, Lemes R, Caires-Junior L, Goulart E, et al.
Tumour Biol . 2020 Dec; 42(12):1010428320977124. PMID: 33256542
Hepatoblastomas exhibit the lowest mutational burden among pediatric tumors. We previously showed that epigenetic disruption is crucial for hepatoblastoma carcinogenesis. Our data revealed hypermethylation of nicotinamide N-methyltransferase, a highly expressed...
7.
de Oliveira A, de Souza G, Guimaraes C, Guimaraes M, da Costa C, de Gobbi Porto F, et al.
PLoS One . 2020 Aug; 15(8):e0238166. PMID: 32853252
Background: The purpose of this study was to determine whether whole-body MRI (WBMRI) with diffusion-weighted sequences, which is free of ionizing radiation, can perform as well as traditional methods when...
8.
Brandi Gomes Godoy P, Mello C, Pompeia S, da Costa C, Cypriano M, Suchecki D
Appl Neuropsychol Child . 2020 Aug; 11(3):270-279. PMID: 32787697
Pediatric cancer treatment can negatively impact cognitive and psychosocial development, although it has been suggested that these adverse effects may be minimized when children have higher resilience and better executive...
9.
Aguiar T, Rivas M, Costa S, Maschietto M, Rodrigues T, Sobral de Barros J, et al.
Front Oncol . 2020 May; 10:556. PMID: 32432034
Hepatoblastoma is a very rare embryonal liver cancer supposed to arise from the impairment of hepatocyte differentiation during embryogenesis. In this study, we investigated by exome sequencing the burden of...
10.
Rivas M, Aguiar T, Fernandes G, Caires-Junior L, Goulart E, Telles-Silva K, et al.
Front Genet . 2019 Jun; 10:553. PMID: 31249594
Hepatoblastoma is an embryonal liver tumor carrying few genetic alterations. We previously disclosed in hepatoblastomas a genome-wide methylation dysfunction, characterized by hypermethylation at specific CpG islands, in addition to a...