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Cecilia M Sahlgren

Explore the profile of Cecilia M Sahlgren including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 481
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Recent Articles
1.
Jouybar M, Sleeboom J, Vaezzadeh E, Sahlgren C, den Toonder J
Front Bioeng Biotechnol . 2023 Dec; 11:1267021. PMID: 38076430
Metastasis is a multi-step process that is critically affected by cues from the tumor micro-environment (TME), such as from the extracellular matrix (ECM). The role of the ECM in the...
2.
Grolleman J, van Engeland N, Raza M, Azimi S, Conte V, Sahlgren C, et al.
Sci Rep . 2023 Oct; 13(1):18374. PMID: 37884575
Recent experimental evidence indicates a role for the intermediate filament vimentin in regulating cellular mechanical homeostasis, but its precise contribution remains to be discovered. Mechanical homeostasis requires a balanced bi-directional...
3.
Mostert D, Grolleman J, van Turnhout M, Groenen B, Conte V, Sahlgren C, et al.
Front Cell Dev Biol . 2023 Oct; 11:1267822. PMID: 37779894
Ventral actin stress fibers (SFs) are a subset of actin SFs that begin and terminate at focal adhesion (FA) complexes. Ventral SFs can transmit forces from and to the extracellular...
4.
Bril M, Saberi A, Jorba I, van Turnhout M, Sahlgren C, Bouten C, et al.
Adv Sci (Weinh) . 2023 Sep; 10(31):e2303136. PMID: 37740666
The extracellular environment defines a physical boundary condition with which cells interact. However, to date, cell response to geometrical environmental cues is largely studied in static settings, which fails to...
5.
van Asten J, Latorre M, Karakaya C, Baaijens F, Sahlgren C, Ristori T, et al.
Biomech Model Mechanobiol . 2023 Apr; 22(5):1569-1588. PMID: 37024602
Blood vessels grow and remodel in response to mechanical stimuli. Many computational models capture this process phenomenologically, by assuming stress homeostasis, but this approach cannot unravel the underlying cellular mechanisms....
6.
Karakaya C, van Turnhout M, Visser V, Ristori T, Bouten C, Sahlgren C, et al.
Front Cell Dev Biol . 2022 Aug; 10:910503. PMID: 36036000
Mechanical stimuli experienced by vascular smooth muscle cells (VSMCs) and mechanosensitive Notch signaling are important regulators of vascular growth and remodeling. However, the interplay between mechanical cues and Notch signaling,...
7.
van Asten J, Ristori T, Nolan D, Lally C, Baaijens F, Sahlgren C, et al.
J Mech Behav Biomed Mater . 2022 Jul; 133:105325. PMID: 35839633
Arteries grow and remodel in response to mechanical stimuli. Hypertension, for example, results in arterial wall thickening. Cell-cell Notch signaling between vascular smooth muscle cells (VSMCs) is known to be...
8.
Tiemeijer L, Ristori T, Stassen O, Ahlberg J, de Bijl J, Chen C, et al.
iScience . 2022 May; 25(5):104306. PMID: 35602952
Spatial regulation of angiogenesis is important for the generation of functional engineered vasculature in regenerative medicine. The Notch ligands Jag1 and Dll4 show distinct expression patterns in endothelial cells and,...
9.
Tiemeijer L, Sanlidag S, Bouten C, Sahlgren C
Trends Biotechnol . 2022 Feb; 40(8):945-957. PMID: 35181146
Recreating functional tissues through bioengineering strategies requires steering of complex cell fate decisions. Notch, a juxtacrine signaling pathway, regulates cell fate and controls cellular organization with local precision. The engineering-friendly...
10.
Karakaya C, van Asten J, Ristori T, Sahlgren C, Loerakker S
Biomech Model Mechanobiol . 2021 Oct; 21(1):5-54. PMID: 34613528
Cardiovascular tissue engineering (CVTE) aims to create living tissues, with the ability to grow and remodel, as replacements for diseased blood vessels and heart valves. Despite promising results, the (long-term)...