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Cathy C Moore

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Recent Articles
1.
Ferreira E, Moore C, Ogereau D, Suwalski A, Prigent S, Rogers R, et al.
Mol Ecol . 2024 Dec; 34(3):e17627. PMID: 39690859
During the early stages of local adaptation and speciation, genetic differences tend to accumulate at certain regions of the genome leading to the formation of genomic islands of divergence (GIDs)....
2.
Rogers R, Grizzard S, Titus-McQuillan J, Bockrath K, Patel S, Wares J, et al.
Mol Ecol . 2020 Dec; 30(5):1155-1173. PMID: 33382161
Freshwater unionid bivalves currently face severe anthropogenic challenges. Over 70% of species in the United States are threatened, endangered or extinct due to pollution, damming of waterways and overfishing. These...
3.
Maltz R, Keirsey J, Kim S, Mackos A, Gharaibeh R, Moore C, et al.
J Pediatr Gastroenterol Nutr . 2018 Dec; 68(4):533-540. PMID: 30540706
Objectives: Gastrointestinal disorders, such as inflammatory bowel diseases (IBDs) and functional gastrointestinal disorders (FGIDs), involve disrupted homeostatic interactions between the microbiota and the host. Both disorders are worsened during stress,...
4.
Maltz R, Keirsey J, Kim S, Mackos A, Gharaibeh R, Moore C, et al.
PLoS One . 2018 May; 13(5):e0196961. PMID: 29742146
Stressor-exposure has been shown to exacerbate inflammation and change the composition of the gastrointestinal microbiota; however stressor-induced effects on microbiota-derived metabolites and their receptors are unknown. Thus, bacterial-produced short chain...
5.
Moore C, McKillop I, Huynh T
J Surg Res . 2012 Sep; 182(1):116-26. PMID: 22940033
Background: Sepsis induces systemic stress by augmenting inflammatory and procoagulant responses, resulting in microvascular dysfunction and end organ failure, events modulated by the protein C pathway. MicroRNAs (miRNAs) are small...
6.
Montegudo A, Palilonis M, Moore C, Huynh T, McKillop I, Evans S
J Surg Res . 2012 May; 179(1):e149-55. PMID: 22560856
Background: Hemorrhagic shock is a life threatening condition characterized by diminishing organ function. The aim of this study was to determine whether an effective pyrrolidine dithiocarbamate (PDTC) treatment protocol could...
7.
Keller S, Moore C, Clemens M, McKillop I, Huynh T
Shock . 2011 Sep; 36(4):361-9. PMID: 21897335
Activated protein C (aPC) promotes fibrinolysis while inhibiting coagulation and inflammation. In septic patients, aPC levels are depleted, and aPC treatment has emerged as a therapeutic option. To better understand...
8.
Moore C, Lakner A, Yengo C, Schrum L
World J Hepatol . 2011 Aug; 3(7):184-97. PMID: 21866250
Aim: To identify and characterize the function of nonmuscle myosin II (NMM II) isoforms in primary rat hepatic stellate cells (HSCs). Methods: Primary HSCs were isolated from male Sprague-Dawley rats...
9.
Keller S, Moore C, Evans S, McKillop I, Huynh T
J Surg Res . 2011 Mar; 168(1):e103-9. PMID: 21429520
Background: Activated protein C (aPC) confers survival benefit in patients with sepsis, yet its protective mechanism(s) remain unclear. Herein, we determined time-dependent severity of renal dysfunction during polymicrobial sepsis. We...
10.
Day S, Lakner A, Moore C, Yen M, Clemens M, Wu E, et al.
Biochem Pharmacol . 2011 Feb; 81(8):996-1003. PMID: 21291870
Hepatic fibrosis is characterized by excess type I collagen deposition and exacerbated inflammatory response. Naltrexone, an opioid receptor antagonist used for treating alcohol abuse, attenuates hepatocellular injury in fibrotic animal...