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Catherine Guenther

Explore the profile of Catherine Guenther including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 419
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Recent Articles
1.
Swami T, Shams A, Mittelstadt M, Guenther C, Tse T, Noor H, et al.
BMJ Open Qual . 2023 Jun; 12(2). PMID: 37263736
Background: Early detection of patients with clinical deterioration admitted to the hospital is critical. The early warning system (EWS) is developed to identify early clinical deterioration. Using individual patient's vital...
2.
McLean C, Reno P, Pollen A, Bassan A, Capellini T, Guenther C, et al.
Nature . 2011 Mar; 471(7337):216-9. PMID: 21390129
Humans differ from other animals in many aspects of anatomy, physiology, and behaviour; however, the genotypic basis of most human-specific traits remains unknown. Recent whole-genome comparisons have made it possible...
3.
Guenther C, Pantalena-Filho L, Kingsley D
PLoS Genet . 2008 Dec; 4(12):e1000308. PMID: 19096511
Cartilage and bone are formed into a remarkable range of shapes and sizes that underlie many anatomical adaptations to different lifestyles in vertebrates. Although the morphological blueprints for individual cartilage...
4.
Menke D, Guenther C, Kingsley D
Development . 2008 Jun; 135(15):2543-53. PMID: 18579682
The Tbx4 transcription factor is crucial for normal hindlimb and vascular development, yet little is known about how its highly conserved expression patterns are generated. We have used comparative genomics...
5.
Feldman G, Billings P, Patel R, Caron R, Guenther C, Kingsley D, et al.
Am J Med Genet A . 2007 Mar; 143A(7):699-706. PMID: 17345627
Bone morphogenetic proteins (BMPs) are a highly conserved class of signaling molecules that induce ectopic cartilage and bone formation in vivo. Dysregulated expression of bone morphogenetic protein 4 (BMP4) is...
6.
Gurley K, Chen H, Guenther C, Nguyen E, Rountree R, Schoor M, et al.
J Bone Miner Res . 2006 Jul; 21(8):1238-47. PMID: 16869722
Unlabelled: To reveal the ANK complete loss of function phenotype in mice, we generated conditional and null alleles. Mice homozygous for the null allele exhibited widespread joint mineralization, similar in...
7.
Frank C, Hawkins N, Guenther C, Horvitz H, Garriga G
Dev Biol . 2005 Jun; 284(2):301-10. PMID: 15979607
Asymmetric cell division occurs when a mother cell divides to generate two distinct daughter cells, a process that promotes the generation of cellular diversity in metazoans. During Caenorhabditis elegans development,...
8.
Mortlock D, Guenther C, Kingsley D
Genome Res . 2003 Aug; 13(9):2069-81. PMID: 12915490
Regulatory sequences in higher genomes can map large distances from gene coding regions, and cannot yet be identified by simple inspection of primary DNA sequence information. Here we describe an...