Catherine E Richter
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Explore the profile of Catherine E Richter including associated specialties, affiliations and a list of published articles.
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8
Citations
98
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Recent Articles
1.
Azhwar R, Richter C, Griffin M, Emly S, Yaman M, Arruda V, et al.
Blood Adv
. 2025 Mar;
PMID: 40085950
Deficiencies in coagulation factor VIII (FVIII, F8) result in the bleeding disorder hemophilia A. An emerging novel therapeutic strategy for bleeding disorders is to enhance hemostasis by limiting natural anticoagulants,...
2.
Richter C, Raghunath A, Griffin M, Yaman M, Arruda V, Samelson-Jones B, et al.
bioRxiv
. 2025 Feb;
PMID: 39896458
Deficiencies in coagulation factor VIII (FVIII, ) result in the bleeding disorder hemophilia A. An emerging novel therapeutic strategy for bleeding disorders is to enhance hemostasis by limiting natural anticoagulants,...
3.
Grzegorski S, Zhao Y, Richter C, Ku C, Lavik K, Paul D, et al.
PLoS Genet
. 2022 Nov;
18(11):e1010534.
PMID: 36449521
Tissue factor (TF) is an evolutionarily conserved protein necessary for initiation of hemostasis. Zebrafish have two copies of the tissue factor gene (f3a and f3b) as the result of an...
4.
Freire C, Fish R, Vilar R, Di Sanza C, Grzegorski S, Richter C, et al.
Blood Adv
. 2020 Nov;
4(21):5480-5491.
PMID: 33166405
Plasma fibrinogen molecules comprise 2 copies of Aα, Bβ, and γ chains folded into a hexameric protein. A minor fibrinogen isoform with an extended Aα chain (AαE) is more abundant...
5.
Bando H, Gergics P, Bohnsack B, Toolan K, Richter C, Shavit J, et al.
Hum Mol Genet
. 2020 Apr;
29(10):1648-1657.
PMID: 32277752
Combined pituitary hormone deficiency (CPHD) is a genetically heterogeneous disorder caused by mutations in over 30 genes. The loss-of-function mutations in many of these genes, including orthodenticle homeobox 2 (OTX2),...
6.
Weyand A, Grzegorski S, Rost M, Lavik K, Ferguson A, Menegatti M, et al.
Blood Adv
. 2019 Jun;
3(11):1670-1680.
PMID: 31167819
In humans, coagulation factor V (FV) deficiency is a rare, clinically heterogeneous bleeding disorder, suggesting that genetic modifiers may contribute to disease expressivity. Zebrafish possess many distinct advantages including high...
7.
Hu Z, Lavik K, Liu Y, Vo A, Richter C, Di Paola J, et al.
J Thromb Haemost
. 2019 Jan;
17(4):607-617.
PMID: 30663848
Essentials Loss of fibrinogen in zebrafish has been previously shown to result in adult onset hemorrhage Hemostatic defects were discovered in early fga embryos but well tolerated until adulthood Afibrinogenemia...
8.
Nfe2 is dispensable for early but required for adult thrombocyte formation and function in zebrafish
Rost M, Shestopalov I, Liu Y, Vo A, Richter C, Emly S, et al.
Blood Adv
. 2018 Dec;
2(23):3418-3427.
PMID: 30504234
The NFE2 transcription factor is expressed in multiple hematopoietic lineages with a well-defined role in regulating megakaryocyte biogenesis and platelet production in mammals. Mice deficient in NFE2 develop severe thrombocytopenia...
9.
Hu Z, Liu Y, Huarng M, Menegatti M, Reyon D, Rost M, et al.
Blood
. 2017 Jun;
130(5):666-676.
PMID: 28576875
Deficiency of factor X (F10) in humans is a rare bleeding disorder with a heterogeneous phenotype and limited therapeutic options. Targeted disruption of and other common pathway factors in mice...
10.
Liu Y, Kretz C, Maeder M, Richter C, Tsao P, Vo A, et al.
Blood
. 2014 May;
124(1):142-50.
PMID: 24782510
Pathologic blood clotting is a leading cause of morbidity and mortality in the developed world, underlying deep vein thrombosis, myocardial infarction, and stroke. Genetic predisposition to thrombosis is still poorly...