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Catherine E Hegarty

Explore the profile of Catherine E Hegarty including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 105
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Recent Articles
1.
Wang H, Liu Z, Nakua H, Hegarty C, Thies M, Patel P, et al.
Biol Psychiatry . 2024 Jun; 97(2):167-177. PMID: 38908657
Background: Patients with early psychosis (EP) (within 3 years after psychosis onset) show significant variability, which makes predicting outcomes challenging. Currently, little evidence exists for stable relationships between neural microstructural...
2.
Wang H, Liu Z, Nakua H, Hegarty C, Thies M, Patel P, et al.
bioRxiv . 2024 May; PMID: 38766080
Background: Early Psychosis patients (EP, within 3 years after psychosis onset) show significant variability, making outcome predictions challenging. Currently, little evidence exists for stable relationships between neural microstructural properties and...
3.
Ianni A, Eisenberg D, Boorman E, Constantino S, Hegarty C, Gregory M, et al.
Nat Commun . 2023 Sep; 14(1):6122. PMID: 37777515
Foraging behavior requires weighing costs of time to decide when to leave one reward patch to search for another. Computational and animal studies suggest that striatal dopamine is key to...
4.
Barth C, Kelly S, Nerland S, Jahanshad N, Alloza C, Ambrogi S, et al.
Mol Psychiatry . 2022 Dec; 28(3):1159-1169. PMID: 36510004
Emerging evidence suggests brain white matter alterations in adolescents with early-onset psychosis (EOP; age of onset <18 years). However, as neuroimaging methods vary and sample sizes are modest, results remain...
5.
Eisenberg D, Kohn P, Hegarty C, Smith N, Grogans S, Czarapata J, et al.
Mol Psychiatry . 2021 Nov; 27(2):1241-1247. PMID: 34789848
Dysregulation of dopamine systems has been considered a foundational driver of pathophysiological processes in schizophrenia, an illness characterized by diverse domains of symptomatology. Prior work observing elevated presynaptic dopamine synthesis...
6.
Hegarty C, Ianni A, Kohn P, Kolachana B, Gregory M, Masdeu J, et al.
Biol Psychiatry Cogn Neurosci Neuroimaging . 2021 Mar; 8(1):121-128. PMID: 33712377
Background: The rs1344706 single nucleotide polymorphism in the ZNF804A gene has been associated with risk for psychosis in multiple genome-wide association studies, yet mechanisms underlying this association are not known....
7.
Barber A, Hegarty C, Lindquist M, Karlsgodt K
Cereb Cortex . 2021 Jan; 31(6):2834-2844. PMID: 33429433
Recent efforts to evaluate the heritability of the brain's functional connectome have predominantly focused on static connectivity. However, evaluating connectivity changes across time can provide valuable insight about the inherent...
8.
Jolles D, Mennigen E, Gupta M, Hegarty C, Bearden C, Karlsgodt K
Neuroimage . 2020 Jul; 221:117202. PMID: 32730958
There are vast individual differences in reading achievement between students. Besides structural and functional variability in domain-specific brain regions, these differences may partially be explained by the organization of domain-general...
9.
Mennigen E, Jolles D, Hegarty C, Gupta M, Jalbrzikowski M, Olde Loohuis L, et al.
Schizophr Bull . 2019 Jun; 46(2):408-421. PMID: 31219595
Psychosis spectrum disorders are conceptualized as neurodevelopmental disorders accompanied by disruption of large-scale functional brain networks. Dynamic functional dysconnectivity has been described in patients with schizophrenia and in help-seeking individuals...
10.
Jalbrzikowski M, Freedman D, Hegarty C, Mennigen E, Karlsgodt K, Olde Loohuis L, et al.
J Am Acad Child Adolesc Psychiatry . 2019 Feb; 58(11):1079-1091. PMID: 30768396
Objective: Adults with established diagnoses of serious mental illness (bipolar disorder and schizophrenia) exhibit structural brain abnormalities, yet less is known about how such abnormalities manifest earlier in development. Method:...