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Cathal M McCarthy

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Articles 18
Citations 296
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Recent Articles
1.
Barron A, Tuulari J, Karlsson L, Karlsson H, OKeeffe G, McCarthy C
Biosci Rep . 2024 Oct; 44(11). PMID: 39474810
Early-onset pre-eclampsia is believed to arise from defective placentation in the first trimester, leading to placental ischaemia/reperfusion (I/R) and oxidative stress. However, our current understanding of the effects of I/R...
2.
Deady C, McCarthy F, Barron A, McCarthy C, OKeeffe G, OMahony S
Front Cell Infect Microbiol . 2024 May; 14:1352267. PMID: 38774629
Hypertensive disorders of pregnancy, including pre-eclampsia, are a leading cause of serious and debilitating complications that affect both the mother and the fetus. Despite the occurrence and the health implications...
3.
Barron A, Barrett L, Tuulari J, Karlsson L, Karlsson H, McCarthy C, et al.
Biosci Rep . 2024 May; 44(5). PMID: 38700092
Pre-eclampsia (PE) is a hypertensive disorder of pregnancy which is associated with increased risk of neurodevelopmental disorders in exposed offspring. The pathophysiological mechanisms mediating this relationship are currently unknown, and...
4.
Morales-Prieto N, Bevans R, OMahony A, Barron A, Giles Doran C, McCarthy E, et al.
Aging Cell . 2024 Mar; 23(6):e14155. PMID: 38529808
Parkinson's disease (PD) is characterised by progressive loss of dopaminergic (DA) neurons from the substantia nigra (SN) and α-synuclein (αSyn) accumulation. Age is the biggest risk factor for PD and...
5.
McElwain C, Manna S, Musumeci A, Sylvester I, Rouchon C, OCallaghan A, et al.
J Clin Endocrinol Metab . 2023 Nov; 109(5):1275-1284. PMID: 38035802
Context: Gestational diabetes mellitus (GDM) is a complex obstetric condition affecting localized glucose metabolism, resulting in systemic metabolic dysfunction. Objective: This cross-sectional study aimed to explore visceral adipose tissue (VAT)...
6.
McElwain C, Musumeci A, Manna S, McCarthy F, McCarthy C
J Reprod Immunol . 2023 Nov; 161:104171. PMID: 38029485
Background: Maternal hyperglycaemia has a significant impact on placental metabolism and mitochondrial function. The NLRP3 inflammasome is responsive to endogenous signals of mitochondrial dysfunction. We tested our hypothesis that mitochondrial...
7.
Barron A, Manna S, McElwain C, Musumeci A, McCarthy F, OKeeffe G, et al.
Front Physiol . 2023 Jan; 13:1043481. PMID: 36714304
Pre-eclampsia (PE) is a common and serious hypertensive disorder of pregnancy, which affects 3%-5% of first-time pregnancies and is a leading cause of maternal and neonatal morbidity and mortality. Prenatal...
8.
McCarthy E, Barron A, Morales-Prieto N, Mazzocchi M, McCarthy C, Collins L, et al.
Mol Neurobiol . 2022 Feb; 59(5):2745-2757. PMID: 35175558
Parkinson's disease (PD) is neurodegenerative disorder with the pathological hallmarks of progressive degeneration of midbrain dopaminergic neurons from the substantia nigra (SN), and accumulation and spread of inclusions of aggregated...
9.
Anantha J, Goulding S, Tuboly E, OMahony A, Moloney G, Lomansey G, et al.
Mol Neurobiol . 2021 Oct; 59(1):61-76. PMID: 34623600
Parkinson's disease (PD) is a neurodegenerative disease characterised by the progressive degeneration of midbrain dopaminergic neurons, coupled with the intracellular accumulation of α-synuclein. Axonal degeneration is a central part of...
10.
McElwain C, McCarthy F, McCarthy C
Int J Mol Sci . 2021 Apr; 22(8). PMID: 33923959
Gestational diabetes mellitus (GDM) is an obstetric complication that affects approximately 5-10% of all pregnancies worldwide. GDM is defined as any degree of glucose intolerance with onset or first recognition...