Caroline T Tiemessen
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Explore the profile of Caroline T Tiemessen including associated specialties, affiliations and a list of published articles.
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127
Citations
1481
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Recent Articles
1.
Tiemessen C
Curr Opin HIV AIDS
. 2025 Feb;
PMID: 39946194
Purpose Of Review: Rare persons who achieve disease-control despite high viral loads (viraemic nonprogressors) or maintain virologic control in the absence of antiretroviral therapy (ART) (elite controllers) or following ART...
2.
Malinga T, Othman H, Paximadis M, Tiemessen C, Ramsay M, Hazelhurst S, et al.
Clin Pharmacol Ther
. 2025 Jan;
PMID: 39829327
Tuberculosis (TB) is a major health burden in Africa. Although TB is treatable, anti-TB drugs are associated with adverse drug reactions (ADRs), which are partly attributed to pharmacogenetic variation. The...
3.
Fortuin T, Nkone P, Glass A, Viana R, Moeng K, Loubser S, et al.
J Virol Methods
. 2024 Sep;
330:115034.
PMID: 39303923
Background: Currently, most HIV drug resistance PCR assays amplify the protease-reverse transcriptase (PR-RT) fragment separately from the integrase (IN) fragment. The aim of this study was to develop a multiplex...
4.
McMahon W, Kwatra G, Izu A, Jones S, Mbele N, Jafta N, et al.
Sci Rep
. 2024 Sep;
14(1):20348.
PMID: 39223211
SARS-CoV-2 cell-mediated immunity remains understudied during pregnancy in unvaccinated Black African women living with HIV (WLWH) from low- and middle-income countries. We investigated SARS-CoV-2-specific T-cell responses 1 month following infection...
5.
HIV-1 Elite Controllers Are Characterized by Elevated Levels of CD69-Expressing Natural Killer Cells
Batohi N, Shalekoff S, Shalekoff S, Martinson N, Ebrahim O, Tiemessen C, et al.
J Acquir Immune Defic Syndr
. 2024 Sep;
97(5):522-532.
PMID: 39219024
Background: HIV type 1 ((human immunodeficiency virus) HIV-1) elite controllers (ECs) are a rare subset of people living with HIV-1 (PLWH) who control viral replication in the absence of antiretroviral...
6.
Kuhn L, Barnabas S, Cotugno N, Peay H, Goulder P, Cotton M, et al.
Lancet HIV
. 2024 Jul;
11(10):e700-e710.
PMID: 39059402
Analytical treatment interruption (ATI) is widely acknowledged as an essential component of studies to advance our understanding of HIV cure, but discussion has largely been focused on adults. To address...
7.
Kae A, Santoro M, Duca L, Ambe Chenwi C, Ngoufack Jagni Semengue E, Nka A, et al.
J Virus Erad
. 2024 Apr;
10(1):100367.
PMID: 38601701
Background: With the advent of antiretroviral therapy (ART), most children living with HIV in sub-Saharan Africa (SSA) are growing toward adolescence, with scarcity of evidence on the size of viral...
8.
Tatoud R, Jones R, Dong K, Ndungu T, Deeks S, Tiemessen C
J Virus Erad
. 2024 Apr;
10(1):100364.
PMID: 38559321
While low- and middle-income countries (LMICs), especially in Southern and Eastern Africa, bear the largest burden of the HIV globally, investigators working on the front lines in these regions are...
9.
Barrios-Tascon A, Strehlau R, Patel F, Burke M, Shiau S, Shen Y, et al.
J Pediatr
. 2024 Mar;
270:114018.
PMID: 38508485
Objective: To investigate the role of early antiretroviral therapy (ART) on growth trajectories of infants with human immunodeficiency virus (IHIV) in the first year of life. Study Design: As part...
10.
Shalekoff S, Dias B, Loubser S, Strehlau R, Kuhn L, Tiemessen C
AIDS
. 2024 Feb;
38(7):945-954.
PMID: 38329228
Objective: CCR5-tropic viruses are preferentially transmitted during perinatal HIV-1 infection. CCR5 density on CD4 + T-cells likely impacts susceptibility to HIV-1 infection. Design: Fifty-two mother-infant dyads were enrolled. All mothers...