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Caroline G Webster

Explore the profile of Caroline G Webster including associated specialties, affiliations and a list of published articles. Areas
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Citations 18
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Recent Articles
1.
Wright N, Matsuoka Y, Park H, He W, Webster C, Furutani K, et al.
Nat Commun . 2024 Dec; 15(1):10738. PMID: 39737929
The current opioid crisis urgently calls for developing non-addictive pain medications. Progress has been slow, highlighting the need to uncover targets with unique mechanisms of action. Extracellular adenosine alleviates pain...
2.
Webster C, Park H, Ennis A, Hong J
Tetrahedron Lett . 2021 May; 71. PMID: 34054153
Rhodojaponin III is a grayanane-type diterpenoid natural product with a novel chemical scaffold. It shows potent antinociceptive activity and may represent a new class of natural non-opioid analgesics with a...
3.
Kwak S, Cochrane C, Ennis A, Lim W, Webster C, Cho J, et al.
Bioorg Chem . 2020 Jul; 102:104055. PMID: 32663666
The UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH is essential in lipid A biosynthesis and has emerged as a promising target for the development of novel antibiotics against multidrug-resistant Gram-negative pathogens. Recently, we...
4.
Cho J, Lee M, Cochrane C, Webster C, Fenton B, Zhao J, et al.
Proc Natl Acad Sci U S A . 2020 Feb; 117(8):4109-4116. PMID: 32041866
The UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH is an essential lipid A biosynthetic enzyme that is conserved in the majority of gram-negative bacteria. It has emerged as an attractive novel antibiotic target...