Caroline Dunk
Overview
Explore the profile of Caroline Dunk including associated specialties, affiliations and a list of published articles.
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29
Citations
684
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Recent Articles
1.
Gilmore J, Hoque M, Dai W, Mohan H, Dunk C, Serghides L, et al.
EBioMedicine
. 2021 Dec;
75:103771.
PMID: 34954655
Background: Due to the critical role of folates in neurodevelopment, it is important to understand potential interactions between anti-HIV drugs used during pregnancy, and folate delivery pathways in the placenta....
2.
Shynlova O, Boros-Rausch A, Farine T, Adams Waldorf K, Dunk C, Lye S
J Immunol
. 2021 Sep;
207(8):2015-2026.
PMID: 34526377
Infiltration of maternal peripheral leukocytes into the uterine tissues is a critical event occurring before, during, and after term labor (TL). In this article, we investigate the contribution of uterine...
3.
Wei Y, Wang T, Ma L, Zhang Y, Zhao Y, Lye K, et al.
Sci Adv
. 2021 Aug;
7(33).
PMID: 34380613
Human trophoblast stem cells (hTSCs) provide a valuable model to study placental development and function. While primary hTSCs have been derived from embryos/early placenta, and transdifferentiated hTSCs from naïve human...
4.
Yampolsky M, Shlakhter O, Deng D, Kala S, Walmsley S, Murphy K, et al.
Placenta
. 2020 Dec;
104:102-109.
PMID: 33310298
Introduction: Women living with HIV experience more adverse birth outcomes; the mechanisms are not fully understood. We examined placenta morphology and associations with birth outcomes in a Canadian cohort of...
5.
Shynlova O, Nadeem L, Zhang J, Dunk C, Lye S
Placenta
. 2020 Sep;
98:29-37.
PMID: 32943204
Term labour is a state of physiological inflammation orchestrated by multiple uterine tissues (both fetal and maternal). This physiological inflammation preceding and accompanying labour onset is characterized by an increase...
6.
Brkic J, Dunk C, Shan Y, OBrien J, Lye P, Qayyum S, et al.
Front Endocrinol (Lausanne)
. 2020 Aug;
11:436.
PMID: 32733385
During placental development, cytotrophoblast progenitor cells differentiate into the syncytiotrophoblast and invasive extravillous trophoblasts (EVTs). Some EVTs further differentiate into endovascular trophoblasts (enEVTs) which exhibit endothelial-like properties. Abnormal placental development,...
7.
Kala S, Dunk C, Acosta S, Serghides L
Hum Reprod
. 2020 Jul;
35(8):1781-1796.
PMID: 32712670
Study Question: Does HIV protease inhibitor (PI)-based combination antiretroviral therapy (cART) initiated at periconception affect key events in early pregnancy, i.e. decidualization and spiral artery remodeling? Summary Answer: Two PIs,...
8.
Shynlova O, Nadeem L, Zhang J, Dunk C, Lye S
Placenta
. 2020 Feb;
92:28-36.
PMID: 32056784
Term labour is a state of physiological inflammation orchestrated by multiple uterine tissues (both fetal and maternal). This physiological inflammation preceding and accompanying labour onset is characterized by an increase...
9.
Xiao L, Shan Y, Ma L, Dunk C, Yu Y, Wei Y
Biochim Biophys Acta Mol Cell Res
. 2019 Aug;
1866(12):118531.
PMID: 31415841
Forkhead box D3 (FOXD3) is a key transcription factor maintaining pluripotency in mouse embryonic stem cells (ESCs). Yet to date studies on its role in human ESCs are quite limited....
10.
Dunk C, Kwan M, Hazan A, Walker S, Wright J, Harris L, et al.
Front Endocrinol (Lausanne)
. 2019 Apr;
10:160.
PMID: 30949130
Failure of uterine vascular transformation is associated with pregnancy complications including Intra Uterine Growth Restriction (IUGR). The decidua and its immune cell populations play a key role in the earliest...