Caroline Dalgliesh
Overview
Explore the profile of Caroline Dalgliesh including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
660
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Recent Articles
1.
Dalgliesh C, Aldalaqan S, Atallah C, Best A, Scott E, Ehrmann I, et al.
EMBO J
. 2025 Jan;
44(3):877-902.
PMID: 39748121
The cellular concentrations of splicing factors (SFs) are critical for controlling alternative splicing. Most serine and arginine-enriched (SR) protein SFs regulate their own concentration via a homeostatic feedback mechanism that...
2.
Siachisumo C, Luzzi S, Aldalaqan S, Hysenaj G, Dalgliesh C, Cheung K, et al.
Elife
. 2024 Oct;
12.
PMID: 39356106
Previously, we showed that the germ cell-specific nuclear protein RBMXL2 represses cryptic splicing patterns during meiosis and is required for male fertility (Ehrmann et al., 2019). Here, we show that...
3.
Advani R, Luzzi S, Scott E, Dalgliesh C, Weischenfeldt J, Munkley J, et al.
Oncogene
. 2023 Sep;
42(43):3161-3168.
PMID: 37752235
Prostate cancer progression is connected to the activity of conventional oncogenes and tumour suppressors and driven by circulating steroid hormones. A key issue has been how to identify and care...
4.
Ramond F, Dalgliesh C, Grimmel M, Wechsberg O, Vetro A, Guerrini R, et al.
Genet Med
. 2022 Dec;
25(4):100003.
PMID: 36549593
Purpose: Transformer2 proteins (Tra2α and Tra2β) control splicing patterns in human cells, and no human phenotypes have been associated with germline variants in these genes. The aim of this work...
5.
Aldalaqan S, Dalgliesh C, Luzzi S, Siachisumo C, Reynard L, Ehrmann I, et al.
Cell Cycle
. 2021 Dec;
21(3):219-227.
PMID: 34927545
High levels of transcription and alternative splicing are recognized hallmarks of gene expression in the testis and largely driven by cells in meiosis. Because of this, the male meiosis stage...
6.
Munkley J, Li L, Krishnan S, Hysenaj G, Scott E, Dalgliesh C, et al.
Elife
. 2019 Sep;
8.
PMID: 31478829
Prostate is the most frequent cancer in men. Prostate cancer progression is driven by androgen steroid hormones, and delayed by androgen deprivation therapy (ADT). Androgens control transcription by stimulating androgen...
7.
Elliott D, Dalgliesh C, Hysenaj G, Ehrmann I
Int J Biochem Cell Biol
. 2018 Dec;
108:1-6.
PMID: 30593955
RBMX is a ubiquitously expressed nuclear RNA binding protein that is encoded by a gene on the X chromosome. RBMX belongs to a small protein family with additional members encoded...
8.
Ehrmann I, Gazzara M, Pagliarini V, Dalgliesh C, Kheirollahi-Chadegani M, Xu Y, et al.
Cell Rep
. 2016 Dec;
17(12):3269-3280.
PMID: 28009295
The brain is made up of trillions of synaptic connections that together form neural networks needed for normal brain function and behavior. SLM2 is a member of a conserved family...
9.
Danilenko M, Dalgliesh C, Pagliarini V, Naro C, Ehrmann I, Feracci M, et al.
Nucleic Acids Res
. 2016 Dec;
45(7):4120-4130.
PMID: 27994030
SLM2 and Sam68 are splicing regulator paralogs that usually overlap in function, yet only SLM2 and not Sam68 controls the Neurexin2 AS4 exon important for brain function. Herein we find...
10.
Feracci M, Foot J, Grellscheid S, Danilenko M, Stehle R, Gonchar O, et al.
Nat Commun
. 2016 Jan;
7:10355.
PMID: 26758068
Sam68 and T-STAR are members of the STAR family of proteins that directly link signal transduction with post-transcriptional gene regulation. Sam68 controls the alternative splicing of many oncogenic proteins. T-STAR...