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Caroline A Lino

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Articles 13
Citations 39
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Recent Articles
1.
Castro E, Vieira T, Peixoto A, Leonardi B, Tomazelli C, Lino C, et al.
Mol Nutr Food Res . 2025 Feb; :e70001. PMID: 39961050
Fish oil rich in omega-3 polyunsaturated fatty acids (n-3 PUFAs) improves rodent glucose homeostasis and insulin sensitivity through unknown mechanisms. We investigated the involvement of adipocyte Rictor/mTORC2 as a mediator...
2.
de Oliveira Silva T, Lunardon G, Lino C, de Almeida Silva A, Zhang S, Irigoyen M, et al.
Mol Metab . 2024 Nov; 91():102065. PMID: 39557194
Objective: We investigated the beneficial effects of a senolytic cocktail (dasatinib and quercetin) on senescence and its influence on obesity-related parameters. Methods And Results: We found that the increase in...
3.
Moretti E, Lino C, Steiner A
Shock . 2024 Apr; 61(6):861-868. PMID: 38662598
There is evidence to suggest that the hypothermia observed in the most severe cases of systemic inflammation or sepsis is a regulated response with potential adaptive value, but the mechanisms...
4.
Balbino-Silva C, Couto G, Lino C, de Oliveira-Silva T, Lunardon G, Huang Z, et al.
Life Sci . 2023 Jan; 316:121416. PMID: 36690245
Aims: Blood vessels are surrounded by perivascular adipose tissue (PVAT), which plays an important role in vascular tonus regulation due to its anticontractile effect; however, this effect is impaired in...
5.
Lino C, de Oliveira-Silva T, Lunardon G, Balbino-Silva C, Lima V, Huang Z, et al.
Mech Ageing Dev . 2023 Jan; 210:111775. PMID: 36641038
High-fat diet (HFD) promotes obesity-related metabolic complications by activating cellular senescence in white adipose tissue (WAT). Growing evidence supports the importance of microRNA-22 (miR-22) in metabolic disorders and cellular senescence....
6.
Lunardon G, de Oliveira Silva T, Lino C, Lu Y, Miranda J, Asprino P, et al.
Clin Sci (Lond) . 2022 Oct; 136(21):1537-1554. PMID: 36285636
Cardiovascular diseases are the main cause of death worldwide. Recent studies have revealed the influence of histone-modifying enzymes in cardiac remodeling and heart dysfunction. The Set7 methyltransferase regulates the expression...
7.
Miranda J, Lunardon G, Lima V, de Oliveira Silva T, Lino C, Jensen L, et al.
Cell Physiol Biochem . 2022 Jul; 56(3):293-309. PMID: 35781359
Background/aims: An obesogenic diet (high fat and sugar, low fiber) is associated with an increased risk for metabolic and cardiovascular disorders. Previous studies have demonstrated that epigenetic changes can modify...
8.
de Oliveira Silva T, Lino C, Miranda J, Balbino-Silva C, Lunardon G, Lima V, et al.
Exp Physiol . 2022 Jun; 107(8):892-905. PMID: 35765992
New Findings: What is the central question of this study? What is the effect of an obesogenic diet on the expression of microRNAs (miRNAs) involved in cardiac hypertrophy in female...
9.
Lima V, Liu J, Brandao B, Lino C, Balbino Silva C, Ribeiro M, et al.
Metabolism . 2021 Feb; 117:154723. PMID: 33549579
Background: Obesity, characterized by excessive expansion of white adipose tissue (WAT), is associated with numerous metabolic complications. Conversely, brown adipose tissue (BAT) and beige fat are thermogenic tissues that protect...
10.
de Oliveira Silva T, Lino C, Buzatto V, Asprino P, Lu Y, Lima V, et al.
Cell Physiol Biochem . 2020 Nov; 54(6):1199-1217. PMID: 33252886
Background/aims: Obesity is a risk factor associated with cardiometabolic complications. Recently, we reported that miRNA-22 deletion attenuated high-fat diet-induced adiposity and prevented dyslipidemia without affecting cardiac hypertrophy in male mice....