Carolina Hassibe Thome
Overview
Explore the profile of Carolina Hassibe Thome including associated specialties, affiliations and a list of published articles.
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Articles
20
Citations
168
Followers
0
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Recent Articles
1.
Rojas C, Pereira-Martins D, Bellido More C, Sternadt D, Weinhauser I, Hilberink J, et al.
Br J Haematol
. 2024 Apr;
204(6):2287-2300.
PMID: 38651345
Despite advancements in utilizing genetic markers to enhance acute myeloid leukaemia (AML) outcome prediction, significant disease heterogeneity persists, hindering clinical management. To refine survival predictions, we assessed the transcriptome of...
2.
Ferreira G, Thome C, Izumi C, Grassi M, Lanfredi G, Smolka M, et al.
J Ovarian Res
. 2023 Nov;
16(1):232.
PMID: 38031074
Background: The epithelial-mesenchymal transition (EMT) promotes cell signaling and morphology alterations, contributing to cancer progression. Exosomes, extracellular vesicles containing proteins involved in cell-cell communication, have emerged as a potential source...
3.
Thome C, Ferreira G, Pereira-Martins D, Augusto Dos Santos G, Almeida-Silveira D, Weinhauser I, et al.
Mol Cell Proteomics
. 2021 May;
20:100091.
PMID: 33971369
Non-T cell activation linker (NTAL) membrane protein depletion from lipid rafts by alkylphospholipids or downregulation by shRNA knockdown decreases cell viability through regulation of the Akt/PI3K pathway in mantle cell...
4.
de Souza L, Ferreira F, Thome C, Brand H, Orellana M, Faca V, et al.
Cancer Lett
. 2020 Dec;
501:114-123.
PMID: 33383153
The mechanisms underlying the propensity of melanomas to metastasize are not completely understood. We hypothesized that melanoma cells are capable of promptly activating an epithelial-to-mesenchymal transition (EMT)-like profile in response...
5.
de Souza A, Bastos V, Fujimura P, Ferreira I, Leal L, Sussuchi da Silva L, et al.
Sci Rep
. 2020 Dec;
10(1):21674.
PMID: 33303880
Cell-free DNA is present in different biological fluids and when released by tumor cells may contribute to pro-tumor events such as malignant transformation of cells adjacent to the tumor and...
6.
Izumi C, Laure H, Barbosa N, Thome C, Ferreira G, Sousa J, et al.
Int J Mol Sci
. 2020 Jul;
21(13).
PMID: 32630308
Gliomas are responsible for more than 60% of all primary brain tumors. Glioblastoma multiforme (GBM), a grade IV tumor (WHO), is one of the most frequent and malignant gliomas. Despite...
7.
Thome C, Ferreira G, Pereira-Martins D, Augusto Dos Santos G, Ortiz C, de Souza L, et al.
Sci Rep
. 2020 Jun;
10(1):10315.
PMID: 32587277
Non-T cell activation linker (NTAL) is a lipid raft-membrane protein expressed by normal and leukemic cells and involved in cell signaling. In acute promyelocytic leukemia (APL), NTAL depletion from lipid...
8.
Silvestrini V, Thome C, Albuquerque D, de Souza Palma C, Ferreira G, Lanfredi G, et al.
J Proteomics
. 2020 Mar;
219:103734.
PMID: 32201364
Epithelial to Mesenchymal Transition (EMT) is a normal cellular process that is also triggered during cancer progression and metastasis. EMT induces cellular and microenviromental changes, resulting in loss of epithelial...
9.
Sangiorgi B, de Souza F, Lima I, Lilian Dos Santos Schiavinato J, Corveloni A, Thome C, et al.
Front Oncol
. 2019 Dec;
9:1100.
PMID: 31788442
Head and neck squamous cell carcinoma (HNSCC) is among the most common cancer types. Metastasis, the main cause of death by cancer, can be promoted by an inflammatory microenvironment, which...
10.
Silvestrini V, Lanfredi G, Masson A, Poersch A, Ferreira G, Thome C, et al.
Mol Omics
. 2019 Aug;
15(5):316-330.
PMID: 31429845
The main cause of death in cancer is the spread, or metastasis, of cancer cells to distant organs with consequent tumor formation. Additionally, metastasis is a process that demands special...