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Carolien Mathyssen

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Recent Articles
1.
Frick A, Orlitova M, Bleeser T, Vanstapel A, Claes S, Schols D, et al.
Eur J Cardiothorac Surg . 2022 Oct; 63(1). PMID: 36214633
Objectives: Primary graft dysfunction resulting from ischaemia-reperfusion injury remains a major obstacle after lung transplantation (LTx) and is associated with morbidity and mortality. Continuous release of inflammatory cytokines, due to...
2.
Serre J, Mathyssen C, Ajime T, Heigl T, Verlinden L, Maes K, et al.
Respir Res . 2022 Mar; 23(1):76. PMID: 35351141
Background: Evidence supports a critical role of vitamin D status on exacerbation in chronic obstructive pulmonary disease, indicating the need to avoid vitamin D deficiency in these patients. However, oral...
3.
Serre J, Tanjeko A, Mathyssen C, Heigl T, Sacreas A, Cook D, et al.
Respir Res . 2022 Mar; 23(1):40. PMID: 35236342
Background: In chronic obstructive pulmonary disease (COPD), exacerbations cause acute inflammatory flare-ups and increase the risk for hospitalization and mortality. Exacerbations are common in all disease stages and are often...
4.
Serre J, Tanjeko A, Mathyssen C, Vanherwegen A, Heigl T, Janssen R, et al.
Respir Res . 2021 Mar; 22(1):86. PMID: 33731130
Background: Chronic obstructive pulmonary disease (COPD) is characterized by a progressive and abnormal inflammatory response in the lungs, mainly caused by cigarette smoking. Animal models exposed to cigarette smoke (CS)...
5.
Janssen R, Serre J, Piscaer I, Zaal R, van Daal H, Mathyssen C, et al.
ERJ Open Res . 2020 Oct; 6(4). PMID: 33043047
Background: Vitamin D supplementation lowers exacerbation frequency in severe vitamin D-deficient patients with COPD. Data regarding the effect of vitamin D on elastin degradation are lacking. Based on the vitamin's...
6.
Mathyssen C, Aelbrecht C, Serre J, Everaerts S, Maes K, Gayan-Ramirez G, et al.
Respir Res . 2020 Jun; 21(1):137. PMID: 32493333
Treatment of Chronic Obstructive Pulmonary Disease (COPD) is based on bronchodilation, with inhaled corticosteroids or azithromycin associated when frequent exacerbations occur. Despite the proven benefits of current treatment regimens, the...
7.
Ghosh M, Murugadoss S, Janssen L, Cokic S, Mathyssen C, van Landuyt K, et al.
J Hazard Mater . 2019 Dec; 387:121691. PMID: 31791862
Given the recent development in the field of particle and fibre toxicology, parallels have been drawn between Carbon nanotubes (CNTs) and asbestos. It is now established that both multi-walled (MWCNTs)...
8.
Mathyssen C, Serre J, Sacreas A, Everaerts S, Maes K, Verleden S, et al.
Nutrients . 2019 Sep; 11(9). PMID: 31500220
In chronic obstructive pulmonary disease (COPD), the bronchial epithelium is the first immune barrier that is triggered by cigarette smoke. Although vitamin D (vitD) has proven anti-inflammatory and antimicrobial effects...
9.
Everaerts S, McDonough J, Verleden S, Josipovic I, Boone M, Dubbeldam A, et al.
Eur Respir J . 2019 Aug; 54(5). PMID: 31467117
The pathophysiological processes underlying bronchiectasis in chronic obstructive pulmonary disease (COPD) are not understood. In COPD, both small and large airways are progressively lost. It is currently not known to...
10.
Maes K, Serre J, Mathyssen C, Janssens W, Gayan-Ramirez G
Calcif Tissue Int . 2019 Jul; 106(1):76-87. PMID: 31350569
Patients with respiratory diseases such as cystic fibrosis, chronic obstructive pulmonary disease, or asthma often experience an acute worsening of respiratory symptoms, termed exacerbations. Although the course of exacerbations is...