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Carola Porcile

Explore the profile of Carola Porcile including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 852
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Recent Articles
1.
Passarella D, Ciampi S, Di Liberto V, Zuccarini M, Ronci M, Medoro A, et al.
Int J Mol Sci . 2022 Aug; 23(16). PMID: 36012187
The low-density-lipoprotein receptors represent a family of pleiotropic cell surface receptors involved in lipid homeostasis, cell migration, proliferation and differentiation. The family shares common structural features but also has significant...
2.
Passarella D, Ronci M, Di Liberto V, Zuccarini M, Mudo G, Porcile C, et al.
Int J Mol Sci . 2022 Aug; 23(15). PMID: 35955821
Recent studies have highlighted the mechanisms controlling the formation of cerebral cholesterol, which is synthesized in situ primarily by astrocytes, where it is loaded onto apolipoproteins and delivered to neurons...
3.
Medoro A, Passarella D, Mignogna D, Porcile C, Fodera E, Intrieri M, et al.
Medicina (Kaunas) . 2022 May; 58(5). PMID: 35630109
Nowadays, novel oral anticoagulants (NOACs) have shown improved safety profile and efficacy compared to vitamin K antagonists in the prevention of thromboembolic events occurring during different pathological conditions. However, there...
4.
Fierro C, Medoro A, Mignogna D, Porcile C, Ciampi S, Fodera E, et al.
Medicina (Kaunas) . 2022 Jan; 58(1). PMID: 35056444
We thank Dr. Sagliocco and Dr. Betelli for their comments [...].
5.
Fierro C, Medoro A, Mignogna D, Porcile C, Ciampi S, Fodera E, et al.
Medicina (Kaunas) . 2021 Jan; 57(1). PMID: 33477765
Sugammadex is a modified γ-cyclodextrin largely used to prevent postoperative residual neuromuscular blockade induced by neuromuscular aminosteroid blocking agents. Although Sugammadex is considered more efficacious and safer than other drugs,...
6.
Medoro A, Bartollino S, Mignogna D, Marziliano N, Porcile C, Nizzari M, et al.
J Alzheimers Dis . 2019 Mar; 68(3):931-938. PMID: 30814362
Certain proteases are involved in Alzheimer's disease (AD) and their erroneous control may contribute to the pathology onset and progression. In this study we evaluated the cerebral expression of eight...
7.
Di Zazzo E, Polito R, Bartollino S, Nigro E, Porcile C, Bianco A, et al.
Int J Mol Sci . 2019 Feb; 20(4). PMID: 30781341
Adipose tissue is a key regulator of energy balance playing an active role in lipid storage as well as in synthesizing several hormones directly involved in the pathogenesis of obesity....
8.
Thellung S, Scoti B, Corsaro A, Villa V, Nizzari M, Gagliani M, et al.
Cell Death Dis . 2018 Feb; 9(2):166. PMID: 29416016
According to the "gain-of-toxicity mechanism", neuronal loss during cerebral proteinopathies is caused by accumulation of aggregation-prone conformers of misfolded cellular proteins, although it is still debated which aggregation state actually...
9.
Medoro A, Bartollino S, Mignogna D, Passarella D, Porcile C, Pagano A, et al.
J Alzheimers Dis . 2017 Nov; 61(1):1-15. PMID: 29103038
The processing of the amyloid-β protein precursor (AβPP) by β- and γ-secretases is a pivotal event in the genesis of Alzheimer's disease (AD). Besides familial mutations on the AβPP gene,...
10.
Corso G, Cristofano A, Sapere N, la Marca G, Angiolillo A, Vitale M, et al.
Dement Geriatr Cogn Dis Extra . 2017 Jun; 7(1):143-159. PMID: 28626469
Background/aims: Abnormalities in the plasma amino acid profile have been reported in Alzheimer disease (AD), but no data exist for the prodromal phase characterized by subjective memory complaint (SMC). It...