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Carmen Urbich

Explore the profile of Carmen Urbich including associated specialties, affiliations and a list of published articles. Areas
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Articles 69
Citations 7771
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Recent Articles
1.
ORourke F, Mandle T, Urbich C, Dimmeler S, Michaelis U, Brandes R, et al.
Cell Microbiol . 2015 Apr; 17(10):1447-63. PMID: 25857345
The contribution of myeloid cells to tumour microenvironments is a decisive factor in cancer progression. Tumour-associated macrophages (TAMs) mediate tumour invasion and angiogenesis through matrix remodelling, immune modulation and release...
2.
Kaluza D, Kroll J, Gesierich S, Manavski Y, Boeckel J, Doebele C, et al.
Arterioscler Thromb Vasc Biol . 2013 Jan; 33(3):533-43. PMID: 23288173
Objective: Histone deacetylases (HDACs) modulate gene expression by deacetylation of histone and nonhistone proteins. Several HDACs control angiogenesis, but the role of HDAC9 is unclear. Methods And Results: Here, we...
3.
Hergenreider E, Heydt S, Treguer K, Boettger T, Horrevoets A, Zeiher A, et al.
Nat Cell Biol . 2012 Feb; 14(3):249-56. PMID: 22327366
The shear-responsive transcription factor Krüppel-like factor 2 (KLF2) is a critical regulator of endothelial gene expression patterns induced by atheroprotective flow. As microRNAs (miRNAs) post-transcriptionally control gene expression in many...
4.
Urbich C, Kaluza D, Fromel T, Knau A, Bennewitz K, Boon R, et al.
Blood . 2011 Dec; 119(6):1607-16. PMID: 22184411
MicroRNAs (miRs) are small RNAs that regulate gene expression at the posttranscriptional level. miR-27 is expressed in endothelial cells, but the specific functions of miR-27b and its family member miR-27a...
5.
Ohtani K, Vlachojannis G, Koyanagi M, Boeckel J, Urbich C, Farcas R, et al.
Circ Res . 2011 Oct; 109(11):1219-29. PMID: 21980126
Rationale: Proangiogenic hematopoietic and endothelial progenitor cells (EPCs) contribute to postnatal neovascularization, but the mechanisms regulating differentiation to the endothelial lineage are unclear. Objective: To elucidate the epigenetic control of...
6.
Kaluza D, Kroll J, Gesierich S, Yao T, Boon R, Hergenreider E, et al.
EMBO J . 2011 Aug; 30(20):4142-56. PMID: 21847094
Histone deacetylases (HDACs) deacetylate histones and non-histone proteins, thereby affecting protein activity and gene expression. The regulation and function of the cytoplasmic class IIb HDAC6 in endothelial cells (ECs) is...
7.
Leistner D, Fischer-Rasokat U, Honold J, Seeger F, Schachinger V, Lehmann R, et al.
Clin Res Cardiol . 2011 Jun; 100(10):925-34. PMID: 21633921
Background: Limited data is available for investigating the long-term safety and effects of intracoronary progenitor cell therapy in patients with acute myocardial infarction (AMI). Objective: To assess the clinical course,...
8.
Urbich C, De Souza A, Rossig L, Yin X, Xing Q, Prokopi M, et al.
J Mol Cell Cardiol . 2010 Dec; 50(2):333-6. PMID: 21147123
Early pro-angiogenic cells (EPCs) have been shown to be involved in neovascularization, angiogenesis and re-endothelialization and cathepsin L inhibition blunted their pro-angiogenic effect. In the present study, we have analysed...
9.
Coffelt S, Tal A, Scholz A, de Palma M, Patel S, Urbich C, et al.
Cancer Res . 2010 Jun; 70(13):5270-80. PMID: 20530679
TIE2-expressing monocytes/macrophages (TEM) are a highly proangiogenic subset of myeloid cells in tumors. Here, we show that circulating human TEMs are already preprogrammed in the circulation to be more angiogenic...
10.
Boon R, Urbich C, Fischer A, Fontijn R, Seeger F, Koyanagi M, et al.
Eur Heart J . 2010 May; 32(3):371-7. PMID: 20494899
Aims: Coronary artery disease (CAD) patients have less circulating proangiogenic cells (PACs), formerly known as endothelial progenitor cells, which exhibit impaired neovascularization properties. Inverse correlations were also found between PAC...