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Carmen S Peden

Explore the profile of Carmen S Peden including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 530
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Recent Articles
1.
Peden C, Manfredsson F, Reimsnider S, Poirier A, Burger C, Muzyczka N, et al.
Mol Ther . 2009 Jan; 17(3):524-37. PMID: 19142181
Recombinant adeno-associated virus (rAAV) expresses no viral genes after transduction. In addition, because the brain is relatively immunoprivileged, intracranial rAAV transduction may be immunologically benign due to a lack of...
2.
Tumer N, Scarpace P, Dogan M, Broxson C, Matheny M, Yurek D, et al.
Neurobiol Aging . 2005 Jun; 27(3):459-70. PMID: 15964099
Intraventricular delivery of glial cell line-derived neurotrophic factor (GDNF) results in weight loss. We hypothesized that this effect of GDNF was likely mediated via its effects on dopaminergic neurons in...
3.
Burger C, Gorbatyuk O, Velardo M, Peden C, Williams P, Zolotukhin S, et al.
Mol Ther . 2004 Aug; 10(2):302-17. PMID: 15294177
Recombinant adeno-associated virus 2 (rAAV2) has been shown to deliver genes to neurons effectively in the brain, retina, and spinal cord. The characterization of new AAV serotypes has revealed that...
4.
Bray C, Cahill K, Oshier J, Peden C, Theriaque D, Flotte T, et al.
J Investig Med . 2004 Jun; 52(3):192-201. PMID: 15222409
Background: Abuse of methylphenidate, a treatment of attention-deficit/hyperactivity disorder, is reported to be increasing among students for the purpose of improving cognition. Methods: A single capsule, containing methylphenidate (20 mg)...
5.
Peden C, Burger C, Muzyczka N, Mandel R
J Virol . 2004 May; 78(12):6344-59. PMID: 15163728
Epidemiological studies report that 80% of the population maintains antibodies (Ab) to wild-type (wt) adeno-associated virus type 2 (AAV2), with 30% expressing neutralizing Ab (NAb). The blood-brain barrier (BBB) provides...
6.
Matalon R, Surendran S, Rady P, Quast M, Campbell G, Matalon K, et al.
Mol Ther . 2003 Apr; 7(5 Pt 1):580-7. PMID: 12718900
Canavan disease (CD) is an autosomal recessive leukodystrophy caused by deficiency of aspartoacylase (ASPA). Deficiency of ASPA leads to elevation of N-acetyl-L-aspartic acid (NAA) in the brain and urine. To...