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Carlos Sao-Jose

Explore the profile of Carlos Sao-Jose including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 966
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Recent Articles
1.
Gouveia A, Pinto D, Vitor J, Sao-Jose C
Int J Mol Sci . 2024 Jan; 25(1). PMID: 38203699
Bacteriophage endolysins are bacteriolytic enzymes that have been explored as potential weapons to fight antibiotic-resistant bacteria. Despite several studies support the application of endolysins as enzybiotics, detailed knowledge on cellular...
2.
Pinto D, Goncalo R, Louro M, Silva M, Hernandez G, Cordeiro T, et al.
Microbiol Spectr . 2022 Jul; 10(4):e0103722. PMID: 35876588
Bacteriophages (phages) and other viruses are extremely efficient in packing their genetic information, with several described cases of overlapping genes encoded in different open reading frames (ORFs). While less frequently...
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Gouveia A, Pinto D, Veiga H, Antunes W, Pinho M, Sao-Jose C
Sci Rep . 2022 Jan; 12(1):1245. PMID: 35075218
Bacteriophage endolysins degrade the bacterial cell wall and are therefore considered promising antimicrobial alternatives to fight pathogens resistant to conventional antibiotics. Gram-positive bacteria are usually considered easy targets to exogenously...
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Fernandes S, Sao-Jose C
Viruses . 2018 Aug; 10(8). PMID: 30060520
Monoderm bacteria possess a cell envelope made of a cytoplasmic membrane and a cell wall, whereas diderm bacteria have and extra lipid layer, the outer membrane, covering the cell wall....
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Sao-Jose C
Antibiotics (Basel) . 2018 Jul; 7(3). PMID: 29973495
The author wishes to make the following corrections to this paper [...].
7.
Oliveira H, Sao-Jose C, Azeredo J
Viruses . 2018 May; 10(6). PMID: 29844287
Peptidoglycan degrading enzymes are of increasing interest as antibacterial agents, especially against multi-drug resistant pathogens. Herein we present a review about the biological features of virion-associated lysins and endolysins, phage-derived...
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Sao-Jose C
Antibiotics (Basel) . 2018 Mar; 7(2). PMID: 29565804
Lytic enzymes encoded by bacteriophages have been intensively explored as alternative agents for combating bacterial pathogens in different contexts. The antibacterial character of these enzymes (enzybiotics) results from their degrading...
9.
Fernandes S, Sao-Jose C
Virology . 2016 Nov; 500:184-189. PMID: 27825035
Double-stranded DNA bacteriophages employ holin and endolysin functions to lyse host bacteria after virus multiplication. Holins oligomerize in the cytoplasmic membrane and trigger to form holes that cause cell death....
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Fernandes S, Sao-Jose C
Mol Microbiol . 2016 Jun; 102(1):92-106. PMID: 27328857
Double-strand DNA bacteriophages employ the holin-endolysin dyad as core components of different strategies to lyse bacterial hosts. In the so-called canonical model the holin holes play an essential role in...